Neoadjuvant treatment for rectal cancerA value-based proposition

被引：4

作者：

Massarweh, Nader N. ^{[1
,2
]}

Artinyan, Avo ^{[2
]}

Chang, George J. ^{[3
,4
]}

机构：

[1] Michael E DeBakey VA Med Ctr, VA Hlth Serv Res & Dev Ctr Innovat Qual Effective, Houston, TX 77030 USA

[2] Baylor Coll Med, Michael E DeBakey Dept Surg, Div Surg Oncol, Houston, TX 77030 USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Surg Oncol, Houston, TX 77030 USA

[4] Univ Texas MD Anderson Canc Ctr, Dept Hlth Serv Res, Houston, TX 77030 USA

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2016年 / 114卷 / 03期

关键词：

rectal cancer; radiation; neoadjuvant; value; TOTAL MESORECTAL EXCISION; SHORT-COURSE RADIOTHERAPY; LOW ANTERIOR RESECTION; QUALITY-OF-LIFE; PREOPERATIVE RADIOTHERAPY; ADJUVANT CHEMOTHERAPY; POSTOPERATIVE CHEMORADIOTHERAPY; ORGAN PRESERVATION; LOCAL RECURRENCE; RANDOMIZED-TRIAL;

D O I：

10.1002/jso.24267

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Over the last decade, the use of neoadjuvant chemo-radiation has been an integral part of the care of patients with locally advanced rectal cancer. However, emerging data are beginning to challenge the current treatment paradigm of neoadjuvant chemo-radiation followed by radical resection and subsequent adjuvant chemotherapy. Going forward, the challenge will be to identify patients for whom radiation can be safely omitted and those for whom it can potentially provide added oncologic value. J. Surg. Oncol. 2016;114:304-310. (c) 2016 Wiley Periodicals, Inc.

引用

页码：304 / 310

页数：7

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