Biornarker responses in caged rockfish (Sebastes schlegeli) from Masan Bay and Haegeumgang, South Korea

被引：17

作者：

Jung, Jee-Hyun ^{[1
]}

Kim, So-Jueng ^{[1
]}

Lee, Taek-Kyun ^{[1
]}

Shim, Won Joon ^{[1
]}

Woo, Seonock ^{[1
]}

Kim, Dae-Jung ^{[2
]}

Han, Chang-Hee ^{[3
]}

机构：

[1] Korean Ocean Res & Dev Inst, S Sea Inst, Geoje 656830, South Korea

[2] NFRDI, Gijang Gun 612902, South Korea

[3] Dong Eui Univ, Div Life Sci, Pusan 614714, South Korea

来源：

MARINE POLLUTION BULLETIN | 2008年 / 57卷 / 6-12期

关键词：

ethoxyresorufin O-deethylase (EROD); rockfish; Sebastes schlegeli; acetyl cholinesterase (AChE); butyryl cholinesterase (BChE); Masan Bay;

D O I：

10.1016/j.marpolbul.2007.12.006

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The purpose of this study was to compare enzymatic biomarker activities in fish caged at two sites, Masan Bay (contaminated) and Haeguemgang (reference). In the present study, ethoxyresorufin O-deethylase (EROD), brain acetyl cholinesterase (bAChE), muscle acetyl cholinesterase (mAChE) and butyryl cholinesterase (mBChE) in caged rockfish (Sebastes schlegeli) were measured 0, 1, 3, 7, 14, 21 and 30 days after caging. The level of CYP1A mRNA and Protein expression was induced higher in Masan Bay at 1, 3, 7, 14 and 30 days after caging. EROD activity in the caged fish was significantly higher in Masan Bay than in Haeguemgang 3 and 7 days after caging, but not at 14 and 30 days after caging. bAChE activity was significantly inhibited at 7 and 14 days after caging in Masan Bay. However, mBChE activity was not significantly inhibited during the experiment. Taken together, the data suggest that the caged fish were exposed, at least transiently, to CYP1A inducers and ChE inhibitors, which is consistent with our previous observations. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：599 / 606

页数：8

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