Recent advances in D-A-D based Pdots with NIR-II fluorescence for deep-tissue imaging

被引：16

作者：

Chowdhury, Partha ^{[1
]}

Chan, Yang-Hsiang ^{[1
,2
,3
]}

机构：

[1] Natl Yang Ming Chiao Tung Univ, Dept Appl Chem, Hsinchu 30050, Taiwan

[2] Natl Yang Ming Chiao Tung Univ, Ctr Emergent Funct Matter Sci, Hsinchu 30050, Taiwan

[3] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 80708, Taiwan

来源：

MOLECULAR SYSTEMS DESIGN & ENGINEERING | 2022年 / 7卷 / 07期

关键词：

SEMICONDUCTING POLYMER DOTS; PHOTOTHERMAL THERAPY; CONJUGATED-POLYMER; RATIONAL DESIGN; CHARGE-TRANSFER; QUANTUM DOTS; NANOPARTICLES; CANCER; NANOMATERIALS; MOLECULES;

D O I：

10.1039/d2me00034b

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In recent years, semiconducting polymer-based nanoparticles (Pdots) emitting in the second near-infrared window (NIR-II, 1000-1700 nm) have become a promising type of ultrabright fluorescence probe benefitting from numerous advantages in the NIR-II region, including reduced photon scattering, minimal tissue autofluorescence, and deep-tissue penetration. Among the diverse types of NIR-II fluorescent Pdots, donor-acceptor-donor (D-A-D)-based Pdots exhibit superior properties over others, especially for their high fluorescent brightness and excellent photostability. This mini-review article focuses on the recent development of D-A-D based Pdots emitting in the NIR-II window and their diverse applications in deep-tissue in vivo imaging. Finally, an outlook is given for the future designs of bright NIR-II D-A-D Pdots.

引用

页码：702 / 719

页数：18

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