Recent advances in D-A-D based Pdots with NIR-II fluorescence for deep-tissue imaging

被引:16
作者
Chowdhury, Partha [1 ]
Chan, Yang-Hsiang [1 ,2 ,3 ]
机构
[1] Natl Yang Ming Chiao Tung Univ, Dept Appl Chem, Hsinchu 30050, Taiwan
[2] Natl Yang Ming Chiao Tung Univ, Ctr Emergent Funct Matter Sci, Hsinchu 30050, Taiwan
[3] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 80708, Taiwan
关键词
SEMICONDUCTING POLYMER DOTS; PHOTOTHERMAL THERAPY; CONJUGATED-POLYMER; RATIONAL DESIGN; CHARGE-TRANSFER; QUANTUM DOTS; NANOPARTICLES; CANCER; NANOMATERIALS; MOLECULES;
D O I
10.1039/d2me00034b
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In recent years, semiconducting polymer-based nanoparticles (Pdots) emitting in the second near-infrared window (NIR-II, 1000-1700 nm) have become a promising type of ultrabright fluorescence probe benefitting from numerous advantages in the NIR-II region, including reduced photon scattering, minimal tissue autofluorescence, and deep-tissue penetration. Among the diverse types of NIR-II fluorescent Pdots, donor-acceptor-donor (D-A-D)-based Pdots exhibit superior properties over others, especially for their high fluorescent brightness and excellent photostability. This mini-review article focuses on the recent development of D-A-D based Pdots emitting in the NIR-II window and their diverse applications in deep-tissue in vivo imaging. Finally, an outlook is given for the future designs of bright NIR-II D-A-D Pdots.
引用
收藏
页码:702 / 719
页数:18
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