Two-channel microelectrochemical bipolar electrode sensor array

被引:75
作者
Chang, Byoung-Yong [3 ]
Chow, Kwok-Fan [1 ,2 ]
Crooks, John A. [1 ,2 ]
Mavre, Francois [1 ,2 ]
Crooks, Richard M. [1 ,2 ]
机构
[1] Univ Texas Austin, Texas Mat Inst, Ctr Electrochem, Dept Chem & Biochem, Austin, TX 78712 USA
[2] Univ Texas Austin, Ctr Nano & Mol Sci & Technol, Austin, TX 78712 USA
[3] Pukyong Natl Univ, Dept Chem, Pusan 608739, South Korea
关键词
ANODIC ELECTROGENERATED CHEMILUMINESCENCE; REDOX REACTIONS; MICROFLUIDIC SENSOR; PHOTONIC REPORTER; ELECTROCHEMILUMINESCENCE; VOLTAMMETRY; HEMOGLOBIN; MICROARRAY; COMPLEXES; OXIDATION;
D O I
10.1039/c2an35382b
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We report a two-channel microelectrochemical sensor that communicates between separate sensing and reporting microchannels via one or more bipolar electrodes (BPEs). Depending on the contents of each microchannel and the voltage applied across the BPE, faradaic reactions may be activated simultaneously in both channels. As presently configured, one end of the BPE is designated as the sensing pole and the other as the reporting pole. When the sensing pole is activated by a target, electrogenerated chemiluminescence (ECL) is emitted at the reporting pole. Compared to previously reported single-channel BPE sensors, the key advantage of the multichannel architecture reported here is physical separation of the ECL reporting cocktail and the solution containing the target. This prevents chemical interference between the two channels.
引用
收藏
页码:2827 / 2833
页数:7
相关论文
共 30 条
[11]   Bipolar Electrodes for Rapid Screening of Electrocatalysts [J].
Fosdick, Stephen E. ;
Crooks, Richard M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (02) :863-866
[12]  
Frantzen F, 1997, CLIN CHEM, V43, P2390
[13]   Coupled Electrochemical Reactions at Bipolar Microelectrodes and Nanoelectrodes [J].
Guerrette, Joshua P. ;
Oja, Stephen M. ;
Zhang, Bo .
ANALYTICAL CHEMISTRY, 2012, 84 (03) :1609-1616
[14]   Generalized theory of steady-state voltammetry without a supporting electrolyte. Effect of product and substrate diffusion coefficient diversity [J].
Hyk, W ;
Stojek, Z .
ANALYTICAL CHEMISTRY, 2002, 74 (18) :4805-4813
[15]   Homogeneous oxidation of trialkylamines by metal complexes and its impact on electrogenerated chemiluminescence in the trialkylamine/Ru(bpy)32+ system [J].
Kanoufi, F ;
Zu, YB ;
Bard, AJ .
JOURNAL OF PHYSICAL CHEMISTRY B, 2001, 105 (01) :210-216
[16]   Electrogenerated chemiluminescence. 65. An investigation of the oxidation of oxalate by tris(polypyridine) ruthenium complexes and the effect of the electrochemical steps on the emission intensity [J].
Kanoufi, F ;
Bard, AJ .
JOURNAL OF PHYSICAL CHEMISTRY B, 1999, 103 (47) :10469-10480
[17]   Shaping and exploring the micro- and nanoworld using bipolar electrochemistry [J].
Loget, Gabriel ;
Kuhn, Alexander .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2011, 400 (06) :1691-1704
[18]   Bipolar Electrodes: A Useful Tool for Concentration, Separation, and Detection of Analytes in Microelectrochemical Systems [J].
Mavre, Francois ;
Anand, Robbyn K. ;
Laws, Derek R. ;
Chow, Kwok-Fan ;
Chang, Byoung-Yong ;
Crooks, John A. ;
Crooks, Richard M. .
ANALYTICAL CHEMISTRY, 2010, 82 (21) :8766-8774
[19]   A Theoretical and Experimental Framework for Understanding Electrogenerated Chemiluminescence (ECL) Emission at Bipolar Electrodes [J].
Mavre, Francois ;
Chow, Kwok-Fan ;
Sheridan, Eoin ;
Chang, Byoung-Yong ;
Crooks, John A. ;
Crooks, Richard M. .
ANALYTICAL CHEMISTRY, 2009, 81 (15) :6218-6225
[20]   Quenching of electrogenerated chemiluminescence by phenols, hydroquinones, catechols, and benzoquinones [J].
McCall, J ;
Alexander, C ;
Richter, MM .
ANALYTICAL CHEMISTRY, 1999, 71 (13) :2523-2527