Hypothermia therapy for cardiac arrest in pediatric patients

被引:19
作者
Hutchison, James S. [1 ,2 ,3 ]
Doherty, Dermot R. [1 ,4 ,5 ]
Orlowski, James P. [6 ]
Kissoon, Niranjan [7 ]
机构
[1] Hosp Sick Children, Dept Crit Care Med, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Crit Care Med, Toronto, ON M5G 1X8, Canada
[3] Hosp Sick Children, Neurosci & Mental Hlth Res Program, Res Inst, Toronto, ON M5G 1X8, Canada
[4] Univ Ottawa, Dept Anesthesia, Ottawa, ON K1H 8L1, Canada
[5] Childrens Hosp Eastern Ontario, Ottawa, ON K1H 8L1, Canada
[6] Univ Community Hosp, Tampa, FL 33613 USA
[7] British Columbia Childrens Hosp, Dept Pediat, Vancouver, BC V6H 3V4, Canada
关键词
D O I
10.1016/j.pcl.2008.02.011
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Cardiac arrest is associated with high morbidity and mortality in children. Hypothermia therapy has theoretical benefits on brain preservation and has the potential to decrease morbidity and mortality in children following cardiac arrest. The American Heart Association guidelines recommend that it should be considered in children after cardiac arrest. Methods of inducing hypothermia include simple surface cooling techniques, intravenous boluses of cold saline, gastric lavage with ice-cold normal saline, and using the temperature control device with extracorporeal life support. We recommend further study before a strong recommendation can be made to use hypothermia therapy in children with cardiac arrest.
引用
收藏
页码:529 / +
页数:17
相关论文
共 102 条
[1]   Phase II clinical trial of moderate hypothermia after severe traumatic brain injury in children [J].
Adelson, PD ;
Ragheb, J ;
Muizelaar, JP ;
Kanev, P ;
Brockmeyer, D ;
Beers, SR ;
Brown, SD ;
Cassidy, LD ;
Chang, YF ;
Levin, H .
NEUROSURGERY, 2005, 56 (04) :740-753
[2]   Neonatal brain protection and deep hypothermic circulatory arrest: pathophysiology of ischemic neuronal injury and protective strategies [J].
Amir, G ;
Ramamoorthy, C ;
Riemer, K ;
Reddy, VM ;
Hanley, FL .
ANNALS OF THORACIC SURGERY, 2005, 80 (05) :1955-1964
[3]   GLUTAMATE-INDUCED NEURONAL DEATH - A SUCCESSION OF NECROSIS OR APOPTOSIS DEPENDING ON MITOCHONDRIAL-FUNCTION [J].
ANKARCRONA, M ;
DYPBUKT, JM ;
BONFOCO, E ;
ZHIVOTOVSKY, B ;
ORRENIUS, S ;
LIPTON, SA ;
NICOTERA, P .
NEURON, 1995, 15 (04) :961-973
[5]   The international liaison committee on resuscitation (ILCOR) consensus on science with treatment recommendations for pediatric and neonatal patients:: Pediatric basic and advanced life support [J].
Atkins, DL ;
Berg, MD ;
Berg, RA ;
Bhutta, AT ;
Biarent, D ;
Bingham, R ;
Braner, D ;
Carrera, R ;
Chameides, L ;
Coovadia, A ;
De Caen, A ;
Diekema, DS ;
Fendya, DG ;
Fiedor, ML ;
Fiser, RT ;
Fuchs, S ;
Gerardi, M ;
Hammill, W ;
Hatch, GW ;
Hazinski, MF ;
Hickey, RW ;
Kattwinkel, J ;
Kleinman, ME ;
López-Herce, J ;
Morley, P ;
Morris, M ;
Nadkarni, VM ;
Nolan, J ;
Perlman, J ;
Proctor, LT ;
Quan, L ;
Reis, AG ;
Richmond, S ;
Rodriguez-Nuñez, A ;
Samson, R ;
Scherer, LR ;
Schexnayder, SM ;
Schleien, CL ;
Shimizu, N ;
Shore, PM ;
Srinivasan, V ;
Stapleton, ER ;
Tibballs, J ;
van der Jagt, EW ;
Zaritsky, A ;
Zideman, D .
PEDIATRICS, 2006, 117 (05) :E955-E977
[6]  
AUER RN, 2002, GREENFIELDS NEUROPAT, P233
[7]   Induced hypothermia using large volume, ice-cold intravenous fluid in comatose survivors of out-of-hospital cardiac arrest: a preliminary report [J].
Bernard, S ;
Buist, M ;
Monteiro, O ;
Smith, K .
RESUSCITATION, 2003, 56 (01) :9-13
[8]   Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia [J].
Bernard, SA ;
Gray, TW ;
Buist, MD ;
Jones, BM ;
Silvester, W ;
Gutteridge, G ;
Smith, K .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (08) :557-563
[9]   Experience with prolonged induced hypothermia in severe head injury [J].
Bernard S.A. ;
Jones B.M. ;
Buist M. .
Critical Care, 3 (6) :167-172
[10]   EFFECT OF HYPOTHERMIA AND CARDIAC-ARREST ON OUTCOME OF NEAR-DROWNING ACCIDENTS IN CHILDREN [J].
BIGGART, MJ ;
BOHN, DJ .
JOURNAL OF PEDIATRICS, 1990, 117 (02) :179-183