Polyarteritis nodosa in association with subarachnoid hemorrhage

被引：21

作者：

Oomura, Masahiro ^{[1
]}

Yamawaki, Takemori ^{[2
]}

Naritomi, Hiroaki ^{[1
]}

Terai, Tadashi ^{[3
]}

Shigeno, Koji ^{[3
]}

机构：

[1] Natl Cardiovasc Ctr, Dept Med, Cerebovasc Div, Osaka 5658565, Japan

[2] Nagoya City Univ, Dept Neurol, Nagoya, Aichi, Japan

[3] Shizuoka Municipal Shimizu Hosp, Dept Neurol, Shizuoka, Japan

来源：

INTERNAL MEDICINE | 2006年 / 45卷 / 09期

关键词：

polyarteritis nodosa; subarachnoid hemorrhage; intracranial aneurysm; ANCA;

D O I：

10.2169/internalmedicine.45.1632

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a 65-year-old man with classic polyarteritis nodosa (PAN) who developed subarachnoid hemorrhage. Polyarteritis nodosa was strongly suspected, however, the biopsy specimens of kidney and sural nerve showed no findings of vasculitis and the serum titer of antimyeloperoxidase-antineutrophil cytoplasmic autoantibody (MPO-ANCA) was negative. Cranial magnetic resonance angiography showed no findings of aneurysms. He developed subarachnoid hemorrhage (SAH) during the course and died. Autopsy confirmed fibrinoid necrosis in the medium-sized artery of multiple organs. To our knowledge, this is the first report of a case of classic PAN accompanied by SAH in which MPO-ANCA proved negative.

引用

页码：655 / 658

页数：4

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