The availability, price and affordability of essential antibacterials in Hubei province, China

被引:14
作者
Wu, Guangjie [1 ,2 ]
Gong, Shiwei [3 ,4 ,5 ]
Cai, Hongbing [3 ,4 ,5 ]
Ding, Yufeng [1 ,2 ]
机构
[1] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Pharm, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
[2] Tongji Hosp, 1095 Jiefang Ave, Wuhan, Hubei, Peoples R China
[3] Huazhong Univ Sci & Technol, Dept Pharm Business & Adm, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
[4] Huazhong Univ Sci & Technol, Sch Pharm, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
[5] Tongji Med Coll, 13 Jiefang Ave, Wuhan, Hubei, Peoples R China
关键词
Essential antibacterials; Availability; Price; Affordability; China; ANTIBIOTIC-RESISTANCE; UNIVERSITY-STUDENTS; ESSENTIAL MEDICINES; MASSIVE MISUSE;
D O I
10.1186/s12913-018-3835-x
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
BackgroundChina ranks first amongst the countries for the abuse of antibacterials. Essential antibacterials could help solve the problem. The aim of the work is to evaluate the availability, price and affordability of essential antibacterials in Hubei province, China.MethodThe standardized methodology developed by the World Health Organization and Health Action International was used to collect data on the availability and prices of 16 antibacterials in 5 cities of Hubei province, China.ResultsFirst, in total, the median availability of originator brands and lowest-priced generics for the essential antibacterials was low, 3.0% (0.0, 18.2%) and 33.3% (0.0, 87.9%) for each, respectively. Second, the median price ratio of originator brands for the antibacterials was 20.30 (4.71, 35.80), while for generics, it was 0.49 (0.07, 1.18). Third, the affordability of originator brands for the antibacterials was 28.14 (21.70, 41.90) times the daily wages of an unskilled government worker, while for generics, the affordability was 0.35 (0.04, 6.11). Finally, we found that in Hubei province, lowest-priced generics for essential antibacterials with (fairly) high availability and relatively low price included Amoxicillin/Clavulanic Acid, Ceftazidime, Metronidazole, Gentamicin Sulfate and Ceftriaxone.ConclusionThe prices of lowest-priced generics for essential antibacterials in Hubei province were reasonable, and in tertiary hospitals the availability was the highest, while in secondary and primary hospitals, it was relatively lower. Originator brands were not only extremely expensive but also difficult to obtain. Measures should be taken to improve the availability of essential antibacterials and the affordability of originator brands.
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页数:8
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