Economic risk coding by single neurons in the orbitofrontal cortex

被引：6

作者：

O'Neill, Martin ^{[1
]}

Schultz, Wolfram ^{[1
]}

机构：

[1] Univ Cambridge, Dept Physiol Dev & Neurosci, Cambridge CB2 3DY, England

来源：

JOURNAL OF PHYSIOLOGY-PARIS | 2015年 / 109卷 / 1-3期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

Risk; Economic; Orbitofrontal cortex; Prediction error; Uncertainty; VENTROMEDIAL PREFRONTAL CORTEX; POSTERIOR CINGULATE CORTEX; DECISION-MAKING; REWARD VALUE; DOPAMINE NEURONS; PROSPECT-THEORY; HUMAN BRAIN; UNCERTAINTY; SALIENCE; REPRESENTATION;

D O I：

10.1016/j.jphysparis.2014.06.002

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Risk is a ubiquitous feature of the environment for all organisms. Very few things in life are achieved with absolute certainty. Therefore, it is essential that organisms process risky information efficiently to promote adaptive behaviour and enhance survival. Here we outline a clear definition of economic risk derived from economic theory and focus on two experiments in which we have shown subpopulations of single neurons in the orbitofrontal cortex of rhesus macaques that code either economic risk per se or an error-related risk signal, namely a risk prediction error. These biological risk signals are essential for processing and updating risky information in the environment to contribute to efficient decision making and adaptive behaviour. (C) 2014 The Authors. Published by Elsevier Ltd.

引用

页码：70 / 77

页数：8

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