Temperature-induced size-control of bioactive surface patterns

被引：42

作者：

Ionov, Leonid ^{[1
]}

Synytska, Alla ^{[2
]}

Diez, Stefan ^{[1
]}

机构：

[1] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany

[2] Leibniz Inst Polymer Res Dresden eV, D-01069 Dresden, Germany

来源：

ADVANCED FUNCTIONAL MATERIALS | 2008年 / 18卷 / 10期

关键词：

D O I：

10.1002/adfm.200800017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present a novel method to produce bioactive surface patterns whose size can be changed in response to a variation of the environmental conditions, rather than local treatment. Our approach is based on the structured surface-immobilization of thermoresponsive poly (N-isopropylacrylamide) (PNIPAM) polymer chains with different transition temperatures. We experimentally demonstrate how the size of an area in which a particular polymer is collapsed or swollen can be controlled by ambient temperature. We show the temperature-induced size-control of a bioactive surface pattern by embedding functional motor proteins into the switchable polymer layers.

引用

页码：1501 / 1508

页数：8

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