Fractionation, preliminary structural characterization and bioactivities of polysaccharides from Sargassum pallidum

被引：108
作者：
Li, Chao [1 ]
Li, Xiangshi [1 ]
You, Lijun [1 ,2 ]
Fu, Xiong [1 ]
Liu, Rui Hai [1 ,2 ]
机构：
[1] South China Univ Technol, Sch Food Sci & Engn, 381 Wushan Rd, Guangzhou 510640, Guangdong, Peoples R China
[2] Cornell Univ, Dept Food Sci, Stocking Hall, Ithaca, NY 14853 USA
来源：
CARBOHYDRATE POLYMERS | 2017年 / 155卷
关键词：
Sargassum pallidum; Polysaccharides; Structural characteristics; Bioactivities; PHENOLIC-RICH EXTRACTS; ALPHA-GLUCOSIDASE; IN-VITRO; ANTIOXIDANT; AMYLASE; IDENTIFICATION; SEAWEED; INHIBITION; ENZYMES; TEA;
D O I：
10.1016/j.carbpol.2016.08.075
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Sargassum pallidum polysaccharides were fractioned using a DEAE-Sepharose fast-flow column and four polysaccharide fractions (SP-P1, SP-P2, PV-P3 and SP-P4) were obtained. Structural analyses indicated that SP-P2 and SP-P4 had higher molecular weights than SP-P1 and SP-P3. SP-P2, SP-P3 and SP-P4 comprised of fucose, rhamnose, arabinose, galactose, glucose, xylose, and mannose in a similar molar ratio, while SP-P1 did not contain arabinose. SP-P2 and SP-P4 had a similar number of (1 -> 6) or (1 ->) glycosidic linkages (1 -> 2) or (1 -> 4) glycosidic linkages and (1 -> 3) glycosidic linkages, while SP-P1 and SP-P3 contained a small number of (1 -> 3) glycosidic linkages. SP-P2 exhibited better bioactivities than SP-P1, SP-P3 and SP-P4, including antioxidant, anti-hemolysis inhibitory, alpha-amylase and alpha-glucosidase inhibitory and antiproliferative activities. These data suggest that S. pallidum has four polysaccharide fractions with different structural features and bioactivities and SP-P2 has potential to be explored as a functional food or complementary medicine. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：261 / 270
页数：10
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