Protolimonoids and quassinoids from Picrolemma granatensis

被引：12
作者：
Fo, ER
Fernandes, JB
Vieira, PC
da Silva, MFGF
ZukermanSchpector, J
deLima, RMOC
Nascimento, SC
Thomas, W
机构：
[1] UNIV FED SAO CARLOS, DEPT QUIM, BR-13565905 SAO CARLOS, SP, BRAZIL
[2] UNIV FED PERNAMBUCO, DEPT ANTIBIOTICOS, BR-50670901 RECIFE, PE, BRAZIL
[3] NEW YORK BOT GARDEN, NEW YORK, NY USA
来源：
PHYTOCHEMISTRY | 1996年 / 43卷 / 04期
基金：
巴西圣保罗研究基金会;
关键词：
Picrolemma granatensis; Simaroubaceae; stem bark; protolimonoids; quassinoids; X-ray analysis; antineoplastic effect;
D O I：
10.1016/0031-9422(96)00348-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
From the stem bark of Picrolemma granatensis three novel triterpenoids were isolated: 7 alpha,24,25-trihydroxy-3-oxo-apotirucalla-14,20(22)-dien and 7 alpha,24,25-trihydroxy-3-oxo-apotirucalla-14,20(22)-dien-21,23-olide and 7 alpha,24,25-trihydroxy-3-apotirucalla-21,23-epoxy-7 alpha,20,21,24,25-pentahydroxyapotirucalla-14-en-3-one which were identified on the basis of spectroscopic and chemical methods and X-ray diffraction. The known quassinoids glaucarubolone, Delta(13,18)-dehydroglaucarubolone, glaucarubinone, glaucarubol, 2'-acetylglaucarubin, excelsin, ailanthinone and holocanthone were also identified. Copyright (C) 1996 Elsevier Science Ltd.
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收藏
页码：857 / 862
页数：6
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