Predictive Analyses of Biological Effects of Natural Products: From Plant Extracts to Biomolecular Laboratory and Computer Modeling

被引：4

作者：

Gambari, Roberto ^{[1
]}

机构：

[1] Dept Biochem & Mol Biol, Mol Biol Sect, I-44100 Ferrara, Italy

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2011年 / 2011卷

关键词：

MEDICINAL-PLANTS; ANTIINFLAMMATORY ACTIVITIES; MOUTAN CORTEX; EXPRESSION; DISCOVERY; CONSTITUENTS; MOLECULES; INDUCERS;

D O I：

10.1093/ecam/nep096

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Year by year, the characterization of the biological activity of natural products is becoming more competitive and complex, with the involvement in this research area of experts belonging to different scientific fields, including chemistry, biochemistry, molecular biology, immunology and bioinformatics. These fields are becoming of great interest for several high-impact scientific journals, including eCAM. The available literature in general, and a survey of reviews and original articles recently published, establishes that natural products, including extracts from medicinal plants and essential oils, retain interesting therapeutic activities, including antitumor, antiviral, anti-inflammatory, pro-apoptotic and differentiating properties. In this commentary, we focus attention on interest in networks based on complementary activation and comparative evaluation of different experimental strategies applied to the discovery and characterization of bioactive natural products. A representative flow chart is shown in the paper.

引用

页码：1 / 4

页数：4

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