LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization

被引:37
作者
Visser-Grieve, Stacy [1 ]
Zhou, Zhonghua [1 ]
She, Yi-Min [2 ]
Huang, He [3 ]
Cyr, Terry D. [2 ]
Xu, Tian [4 ]
Yang, Xiaolong [1 ]
机构
[1] Queens Univ, Dept Pathol & Mol Med, Kingston, ON K7L 3N6, Canada
[2] Hlth Canada, Biol & Genet Therapies Directorate, Ctr Vaccine Res, Ottawa, ON K1A 0K9, Canada
[3] Univ Calif San Diego, Dept Pediat, La Jolla, CA 92093 USA
[4] Yale Univ, Sch Med, Dept Genet, Howard Hughes Med Inst, New Haven, CT 06536 USA
关键词
F-ACTIN; PATHWAY; YAP;
D O I
10.1038/cr.2011.122
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:1513 / 1516
页数:4
相关论文
共 9 条
[1]   The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance [J].
Emoto, Kazuo ;
Parrish, Jay Z. ;
Jan, Lily Yeh ;
Jan, Yuh-Nung .
NATURE, 2006, 443 (7108) :210-213
[2]   The neurofibromatosis 2 protein product merlin selectively binds F-actin but not G-actin, and stabilizes the filaments through a lateral association [J].
James, MF ;
Manchanda, N ;
Gonzalez-Agosti, C ;
Hartwig, JH ;
Ramesh, V .
BIOCHEMICAL JOURNAL, 2001, 356 (356) :377-385
[3]   Wild-type p53 protein shows calcium-dependent binding to F-actin [J].
Metcalfe, S ;
Weeds, A ;
Okorokov, AL ;
Milner, J ;
Cockman, M ;
Pope, B .
ONCOGENE, 1999, 18 (14) :2351-2355
[4]   Regulated binding of adenomatous polyposis coli protein to actin [J].
Moseley, James B. ;
Bartolini, Francesca ;
Okada, Kyoko ;
Wen, Ying ;
Gundersen, Gregg G. ;
Goode, Bruce L. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (17) :12661-12668
[5]   LATS tumor suppressor A new governor of cellular homeostasis [J].
Visser, Stacy ;
Yang, Xiaolong .
CELL CYCLE, 2010, 9 (19) :3892-3903
[6]   Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray [J].
Visser, Stacy ;
Yang, Xiaolong .
GENE, 2010, 449 (1-2) :22-29
[7]   Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/Warts serine/threonine kinase family [J].
Zallen, JA ;
Peckol, EL ;
Tobin, DM ;
Bargmann, CI .
MOLECULAR BIOLOGY OF THE CELL, 2000, 11 (09) :3177-3190
[8]   Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway [J].
Zhang, Jianmin ;
Smolen, Gromoslaw A. ;
Haber, Daniel A. .
CANCER RESEARCH, 2008, 68 (08) :2789-2794
[9]   The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version [J].
Zhao, Bin ;
Li, Li ;
Lei, Qunying ;
Guan, Kun-Liang .
GENES & DEVELOPMENT, 2010, 24 (09) :862-874