One-pot facile synthesis of novel 1,2,3-triazole-appended -aminophosphonates

被引：14

作者：

Danne, Ashruba B. ^{[1
]}

Akolkar, Satish V. ^{[1
]}

Deshmukh, Tejshri R. ^{[1
]}

Siddiqui, Madiha M. ^{[1
]}

Shingate, Bapurao B. ^{[1
]}

机构：

[1] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad 431004, Maharashtra, India

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2019年 / 16卷 / 05期

关键词：

1; 2; 3-Triazole; -Aminophosphonate; Multicomponent reaction; C-P bond formation; ALPHA-AMINO PHOSPHONATES; ANTITUBERCULAR AGENTS SYNTHESIS; SOLVENT-FREE SYNTHESIS; CLICK CHEMISTRY; BIOLOGICAL EVALUATION; 1,3-DIPOLAR CYCLOADDITION; STEREOSELECTIVE-SYNTHESIS; ANTIMICROBIAL ACTIVITY; EFFICIENT SYNTHESIS; ANTITUMOR-ACTIVITY;

D O I：

10.1007/s13738-018-1571-0

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New -aminophosphonates bearing 1,2,3-triazolyl moiety were easily synthesized by one-pot reaction of 1-aryl-1H-1,2,3-triazole-4-carbaldehydes, anilines and trimethyl phosphite in good to excellent yields. All the synthesized compounds were characterized by IR, H-1 NMR and C-13 NMR analysis. These novel 1,2,3-triazole-incorporated -aminophosphonates may be potential biological compounds due to the presence of both important moieties, 1,2,3-triazole and aminophosphonates. [GRAPHICS]

引用

页码：953 / 961

页数：9

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