Three new oxylipins from an Okinawan marine sponge Plakortis sp.

被引：5

作者：

Tanaka, Naonobu ^{[1
,2
]}

Asai, Miki ^{[1
]}

Kusama, Taishi ^{[1
]}

Fromont, Jane ^{[3
]}

Kobayashi, Jun'ichi ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

[2] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan

[3] Western Australian Museum, Welshpool Dc, WA 6986, Australia

来源：

TETRAHEDRON LETTERS | 2015年 / 56卷 / 11期

关键词：

Marine sponge; Plakortis sp; Oxylipin; Manzamenone P; FATTY-ACID DERIVATIVES; MANZAMENONES;

D O I：

10.1016/j.tetlet.2015.01.137

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new oxylipins, manzamenone P (1), 6'-O-methylmanzamenone K (2), and 6'-O-ethylmanzamenone K (3), were isolated from an Okinawan marine sponge Plakortis sp. Manzamenone P (1) is a unique oxylipin possessing two long acyl chains and a novel core unit consisting of spiro-bonded cyclohexanone and beta-keto-gamma-lactone rings. The structures of 1-3 were elucidated on the basis of spectroscopic evidences including 2D NMR and FABMS/MS spectra as well as a comparison of DFT calculated NMR data with those experimental data. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：1388 / 1391

页数：4

共 15 条

[1]

Blunt JW, 2014, NAT PROD REP, V31, P160, DOI [10.1039/c7np00052a, 10.1039/c3np70117d]

[2]

Frisch M. J., 2010, GAUSSIAN 09 REVISION

[3] UNTENONE-A, A NEW CYCLOPENTENONE FROM THE OKINAWAN MARINE SPONGE PLAKORTIS SP CORRESPONDING TO THE DIENOPHILE IN THE BIOSYNTHESIS OF MANZAMENONES [J].