Palladium-catalyzed silylation of aryl chlorides with hexamethyldisilane

被引：76
|
作者：
McNeill, Eric [1 ]
Barder, Timothy E. [1 ]
Buchwald, Stephen L. [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 19期
关键词：
D O I：
10.1021/ol701518f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A method for the palladium-catalyzed silylation of aryl chlorides has been developed. The method affords desired product in good yield, is tolerant of a variety of functional groups, and provides access to a wide variety of aryltrimethylsilanes from commercially available aryl chlorides. Additionally, a one-pot procedure that converts aryl chlorides into aryl iodides has been developed.
引用
收藏
页码：3785 / 3788
页数：4
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