Treatment of spinocerebellar ataxia with buspirone

被引：21
作者：
Assadi, Mitra
Campellone, Joseph V.
Janson, Christopher G.
Veloski, J. Jon
Schwartzman, Robert J.
Leone, Paola
机构：
[1] Cooper Univ Hosp, Robert Wood Johnson Med Sch, Div Neurol, Dept Med, Camden, NJ USA
[2] Cooper Univ Hosp, Robert Wood Johnson Med Sch, Dept Mol Genet, Camden, NJ USA
[3] Thomas Jefferson Univ, Jefferson Med Coll, Ctr Res Med Educ & Hlth Care, Philadelphia, PA 19107 USA
[4] Drexel Univ Hosp, Dept Neurol, Philadelphia, PA USA
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 2007年 / 260卷 / 1-2期
关键词：
ataxia; SCA; buspirone;
D O I：
10.1016/j.jns.2007.04.019
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA. (C) 2007 Elsevier B.V. All rights reserved.
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收藏
页码：143 / 146
页数：4
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