Washout filter based control for the Hodgkin-Huxley nerve cell dynamics

被引:4
作者
Doruk, Resat Oezguer [1 ]
机构
[1] Middle E Tech Univ No Cyprus Kalkanli, KKTC TRNC, Ankara, Turkey
关键词
Hopf bifurcation; saddle bifurcation; Hodgkin-Huxley equation; potassium; channel; sodium channel; BIFURCATION CONTROL; CHAOS;
D O I
10.3906/elk-0904-20
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
In this work we present a washout filler based control approach for stabilizing the oscillations in Hodgkin-Huxley type neurons. The oscillations occur due to the bifurcations that arise from the potassium and sodium channel conductance deviations. The MATCONT toolbox software environment was used for analysis of the bifurcation points in conjunction with MATLAB. The simulations of the Hodgkin-Huxley (HH) model at those points are provided to validate the results obtained from, the MATCONT software. Then a washout filter is proposed to stabilize the oscillations occur at the Hopf bifurcation points where the external current injection is used to provide the control actuation. A second simulation set is provided to demonstrate the action of the washout filter.
引用
收藏
页码:553 / 570
页数:18
相关论文
共 18 条
[1]   STABILIZATION OF PERIOD-DOUBLING BIFURCATIONS AND IMPLICATIONS FOR CONTROL OF CHAOS [J].
ABED, EH ;
WANG, HO ;
CHEN, RC .
PHYSICA D, 1994, 70 (1-2) :154-164
[2]   Bifurcation control of two nonlinear models of cardiac activity [J].
Brandt, ME ;
Chen, GR .
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS, 1997, 44 (10) :1031-1034
[3]   On time-delayed feedback control of chaotic systems [J].
Chen, GR ;
Yu, XH .
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-FUNDAMENTAL THEORY AND APPLICATIONS, 1999, 46 (06) :767-772
[4]   INTRODUCTION TO BIFURCATION-THEORY [J].
CRAWFORD, JD .
REVIEWS OF MODERN PHYSICS, 1991, 63 (04) :991-1037
[5]   MATCONT: A MATLAB package for numerical bifurcation analysis of ODEs [J].
Dhooge, A ;
Govaerts, W ;
Kuznetsov, YA .
ACM TRANSACTIONS ON MATHEMATICAL SOFTWARE, 2003, 29 (02) :141-164
[6]  
GOLDBERGER AL, 1988, J ELECTROCARDIOLOGY, V21
[7]  
HASSOUNEH MA, 2004, WASHOUT FILTERS FEED, P3950
[8]  
HEIDEN U, 2006, PHARMACOPSYCHIATR S1, V39, pS36
[9]   A QUANTITATIVE DESCRIPTION OF MEMBRANE CURRENT AND ITS APPLICATION TO CONDUCTION AND EXCITATION IN NERVE [J].
HODGKIN, AL ;
HUXLEY, AF .
JOURNAL OF PHYSIOLOGY-LONDON, 1952, 117 (04) :500-544
[10]  
HORNG TL, 2006, J MED BIOL ENG, V26, P161