The Global Trachoma Mapping Project: Methodology of a 34-Country Population-Based Study

被引:184
作者
Solomon, Anthony W. [1 ,2 ]
Pavluck, Alexandre L. [3 ]
Courtright, Paul [4 ]
Aboe, Agatha [5 ]
Adamu, Liknaw [6 ]
Alemayehu, Wondu [7 ,8 ]
Alemu, Menbere [9 ]
Alexander, Neal D. E. [10 ]
Kello, Amir Bedri [11 ]
Bero, Berhanu [9 ]
Brooker, Simon J. [1 ,2 ]
Chu, Brian K. [3 ]
Dejene, Michael [12 ]
Emerson, Paul M. [13 ]
Flueckiger, Rebecca M. [3 ]
Gadisa, Solomon [14 ]
Gass, Katherine [3 ]
Gebre, Teshome [15 ]
Habtamu, Zelalem [14 ]
Harvey, Erik [16 ]
Haslam, Dominic [17 ]
King, Jonathan D. [13 ]
Le Mesurier, Richard [18 ]
Lewallen, Susan [4 ]
Lietman, Thomas M. [19 ]
MacArthur, Chad [20 ]
Mariotti, Silvio P. [21 ]
Massey, Anna [17 ]
Mathieu, Els [22 ]
Mekasha, Addis [14 ]
Millar, Tom [17 ]
Mpyet, Caleb [23 ,24 ]
Munoz, Beatriz E. [25 ]
Ngondi, Jeremiah [13 ]
Ogden, Stephanie [3 ]
Pearce, Joseph [16 ]
Sarah, Virginia [18 ]
Sisay, Alemayehu [26 ]
Smith, Jennifer L. [1 ,2 ]
Taylor, Hugh R. [27 ]
Thomson, Jo [18 ]
West, Sheila K. [25 ]
Willis, Rebecca [3 ]
Bush, Simon [5 ]
Haddad, Danny [3 ,28 ]
Foster, Allen [1 ]
机构
[1] Univ London London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London WC1E 7HT, England
[2] London Ctr Neglected Trop Dis Res, London, England
[3] Int Trachoma Initiat, Task Force Global Hlth, Decatur, GA USA
[4] Univ Cape Town, Div Ophthalmol, Kilimanjaro Ctr Community Ophthalmol, ZA-7925 Cape Town, South Africa
[5] Sightsavers, Airport Residential Area, Accra, Ghana
[6] Community Eye Hlth Consultancy, Addis Ababa, Ethiopia
[7] Fred Hollows Fdn Ethiopia, Addis Ababa, Ethiopia
[8] Berhan Publ Hlth & Eye Care Consultancy, Addis Adaba, Ethiopia
[9] Int Trachoma Initiat, Ethiopia Off, Addis Ababa, Ethiopia
[10] Univ London London Sch Hyg & Trop Med, MRC Trop Epidemiol Grp, London WC1E 7HT, England
[11] Light World, Addis Ababa, Ethiopia
[12] Michael Dejene Publ Hlth Consultancy Serv, Addis Ababa, Ethiopia
[13] Emory Univ, Carter Ctr, Atlanta, GA 30322 USA
[14] Oromia Reg Hlth Bur, Addis Ababa, Ethiopia
[15] Int Trachoma Initiat, Reg Off Africa, Addis Ababa, Ethiopia
[16] Water Aid, London, England
[17] Sightsavers, Haywards Heath, W Sussex, England
[18] Fred Hollows Fdn, Rosebery, NSW, Australia
[19] Univ Calif San Francisco, Francis I Proctor Fdn, San Francisco, CA 94143 USA
[20] Helen Keller Int, New York, NY USA
[21] World Hlth Org, Prevent Blindness & Deafness, Geneva, Switzerland
[22] Ctr Dis Control & Prevent, Atlanta, GA USA
[23] Sightsavers Nigeria, Kaduna, Nigeria
[24] Univ Jos, Dept Ophthalmol, Jos, Nigeria
[25] Johns Hopkins Sch Med, Wilmer Inst, Dana Ctr Prevent Ophthalmol, Baltimore, MD USA
[26] ORBIS Int Ethiopia, Addis Ababa, Ethiopia
[27] Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic 3010, Australia
[28] Emory Eye Ctr, Atlanta, GA USA
关键词
Blindness; mHealth; prevalence study; trachoma; trichiasis; NEGLECTED TROPICAL DISEASES; CENTRAL TANZANIA; CONTROL PROGRAMS; MUSCA-SORBENS; EPIDEMIOLOGY; ECOLOGY; VECTOR; SYSTEM; FACE;
D O I
10.3109/09286586.2015.1037401
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To complete the baseline trachoma map worldwide by conducting population-based surveys in an estimated 1238 suspected endemic districts of 34 countries. Methods: A series of national and sub-national projects owned, managed and staffed by ministries of health, conduct house-to-house cluster random sample surveys in evaluation units, which generally correspond to "health district" size: populations of 100,000-250,000 people. In each evaluation unit, we invite all residents aged 1 year and older from h households in each of c clusters to be examined for clinical signs of trachoma, where h is the number of households that can be seen by 1 team in 1 day, and the product h x c is calculated to facilitate recruitment of 1019 children aged 1-9 years. In addition to individual-level demographic and clinical data, household-level water, sanitation and hygiene data are entered into the purpose-built LINKS application on Android smartphones, transmitted to the Cloud, and cleaned, analyzed and ministry-of-health-approved via a secure web-based portal. The main outcome measures are the evaluation unit-level prevalence of follicular trachoma in children aged 1-9 years, prevalence of trachomatous trichiasis in adults aged 15+ years, percentage of households using safe methods for disposal of human feces, and percentage of households with proximate access to water for personal hygiene purposes. Results: In the first year of fieldwork, 347 field teams commenced work in 21 projects in 7 countries. Conclusion: With an approach that is innovative in design and scale, we aim to complete baseline mapping of trachoma throughout the world in 2015.
引用
收藏
页码:214 / 225
页数:12
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