Unexpected right hemisphere language representation identified by the intracarotid amobarbital procedure in right-handed epilepsy surgery candidates

被引：3

作者：

Cunningham, Joseph M. ^{[1
]}

Morris, George L., III ^{[2
]}

Drea, Laura A. ^{[1
]}

Kroll, Jennifer L. ^{[2
]}

机构：

[1] St Lukes Med Ctr, Neuropsychol Serv, Milwaukee, WI 53215 USA

[2] St Lukes Med Ctr, Reg Epilepsy Ctr, Milwaukee, WI 53215 USA

来源：

EPILEPSY & BEHAVIOR | 2008年 / 13卷 / 01期

关键词：

language lateralization; right hemisphere; handedness; temporal lobe epilepsy; intracarotid annobarbital procedure; Wada test;

D O I：

10.1016/j.yebeh.2008.02.019

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The intracarotid amobarbital procedure (IAP) is used for language lateralization in the presurgical evaluation for intractable epilepsy. Some epilepsy surgical centers forgo IAP for right temporal lobectomies in right-handed patients with no personal/family history of left-handedness, implying that right hemisphere language representation does not occur in these patients. To test this hypothesis, a retrospective analysis was performed on 156 consecutive epilepsy surgery candidates who underwent IAP. Of the 156 candidates, 122 were right-handed, and 55 of the 122 demonstrated right hemisphere seizure focus. Right hemisphere language representation was found in 22 of 55 patients, with two demonstrating significant right hemisphere language despite a right hemisphere seizure focus and no family history of left-handedness. Only 1 of 156 patients undergoing IAP experienced permanent neurological complications. Although relatively uncommon, right hemisphere language representation may occur more frequently than complications from cerebral angiography and, therefore, presurgical IAP is recommended for all epilepsy surgery candidates regardless of handedness to minimize the risk of severe language decline. (c) 2008 Elsevier Inc. All rights reserved.

引用

页码：139 / 143

页数：5

共 22 条

[1] Is it time to replace the Wada test? [J].

Abou-Khalil, B ;

Schlaggar, BL .

NEUROLOGY, 2002, 59 (02) :160-161

[2]

Baxendale S, 2003, NEUROLOGY, V60, P354, DOI 10.1212/WNL.60.2.354

[3] Language lateralization in temporal lobe epilepsy:: A comparison between fMRI and the wada test [J].

Benke, Thomas ;

Koylu, Bulent ;

Visani, Pamela ;

Karner, Elfriede ;

Brenneis, Christian ;

Bartha, Lisa ;

Trinka, Eugen ;

Trieb, Thomas ;

Felber, Stephan ;

Bauer, Gerhard ;

Chemelli, Andreas ;

Willmes, Klaus .

EPILEPSIA, 2006, 47 (08) :1308-1319

[4] Determination of language dominance using functional MRI: A comparison with the Wada test [J].

Binder, JR ;

Swanson, SJ ;

Hammeke, TA ;

Morris, GL ;

Mueller, WM ;

Fischer, M ;

Benbadis, S ;

Frost, JA ;

Rao, SM ;

Haughton, VM .

NEUROLOGY, 1996, 46 (04) :978-984

[5] INTRACAROTID SODIUM AMYTAL FOR LATERALIZATION OF CEREBRAL SPEECH DOMINANCE [J].

BRANCH, C ;

MILNER, B ;

RASMUSSEN, T .

JOURNAL OF NEUROSURGERY, 1964, 21 (05) :399-&

[6] Language dominance in partial epilepsy patients identified with an fMRI reading task [J].

Gaillard, WD ;

Balsamo, L ;

Xu, B ;

Grandin, CB ;

Braniecki, SH ;

Papero, PH ;

Weinstein, S ;

Conry, J ;

Pearl, PL ;

Sachs, B ;

Sato, S ;

Jabbari, B ;

Vezina, LG ;

Frattali, C ;

Theodore, WH .

NEUROLOGY, 2002, 59 (02) :256-265

[7] Patterns of language dominance in focal left and right hemisphere epilepsies: Relation to MRI findings, EEG, sex, and age at onset of epilepsy [J].

Helmstaedter, C ;

Kurthen, M ;

Linke, DB ;

Elger, CE .

BRAIN AND COGNITION, 1997, 33 (02) :135-150

[8] Degree of handedness and cerebral dominance [J].

Isaacs, Keren L. ;

Barr, William B. ;

Nelson, Peter Kim ;

Devinsky, Orrin .

NEUROLOGY, 2006, 66 (12) :1855-1858

[9]

Köppel S, 2005, CURR OPIN NEUROL, V18, P418

[10] CEREBRAL LANGUAGE LATERALIZATION - EVIDENCE FROM INTRACAROTID AMOBARBITAL TESTING [J].

LORING, DW ;

MEADOR, KJ ;

LEE, GP ;

MURRO, AM ;

SMITH, JR ;

FLANIGIN, HF ;

GALLAGHER, BB ;

KING, DW .

NEUROPSYCHOLOGIA, 1990, 28 (08) :831-838

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