Persistence of mutant isocitrate dehydrogenase in patients with acute myeloid leukemia in remission

被引：18
作者：
Chou, W-C [1 ,2 ]
Peng, K-Y [3 ,4 ]
Lei, W-C [2 ]
Ko, B-S [2 ]
Tsay, W. [2 ]
Kuo, C-H [3 ,5 ]
Tien, H-F [2 ]
机构：
[1] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Lab Med, Taipei 10764, Taiwan
[2] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Div Hematol, Taipei 10764, Taiwan
[3] Natl Taiwan Univ, Ctr Genom Med, Metabol Core Lab, Taipei 10764, Taiwan
[4] Natl Taiwan Univ, Coll Publ Hlth, Inst Environm Hlth, Taipei 10764, Taiwan
[5] Natl Taiwan Univ, Coll Med, Dept Pharm, Taipei 10764, Taiwan
来源：
LEUKEMIA | 2012年 / 26卷 / 03期
关键词：
INTERNAL TANDEM DUPLICATION; IDH2; MUTATIONS; BEARING; GLIOMAS;
D O I：
10.1038/leu.2011.215
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：527 / 529
页数：3
相关论文
共 15 条
  • [1] Sensitive measurement of quantity dynamics of FLT3 internal tandem duplication at early time points provides prognostic information
    Chou, W. -C.
    Hou, H. -A.
    Liu, C. -Y.
    Chen, C. -Y.
    Lin, L. -I.
    Huang, Y. -N.
    Chao, Y. -C.
    Hsu, C. -A.
    Huang, C. -F.
    Tien, H. -F.
    [J]. ANNALS OF ONCOLOGY, 2011, 22 (03) : 696 - 704
  • [2] Clinical implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nucleophosmin (NPM1) mutations
    Chou, W-C
    Tang, J-L
    Wu, S-J
    Tsay, W.
    Yao, M.
    Huang, S-Y
    Huang, K-C
    Chen, C-Y
    Huang, C-F
    Tien, H-F
    [J]. LEUKEMIA, 2007, 21 (05) : 998 - 1004
  • [3] The prognostic impact and stability of Isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia
    Chou, W-C
    Lei, W-C
    Ko, B-S
    Hou, H-A
    Chen, C-Y
    Tang, J-L
    Yao, M.
    Tsay, W.
    Wu, S-J
    Huang, S-Y
    Hsu, S-C
    Chen, Y-C
    Chang, Y-C
    Kuo, K-T
    Lee, F-Y
    Liu, M-C
    Liu, C-W
    Tseng, M-H
    Huang, C-F
    Tien, H-F
    [J]. LEUKEMIA, 2011, 25 (02) : 246 - 253
  • [4] Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation
    Chou, Wen-Chien
    Hou, Hsin-An
    Chen, Chien-Yuan
    Tang, Jih-Luh
    Yao, Ming
    Tsay, Woei
    Ko, Bor-Shen
    Wu, Shang-Ju
    Huang, Shang-Yi
    Hsu, Szu-Chun
    Chen, Yao-Chang
    Huang, Yen-Ning
    Chang, Yi-Chang
    Lee, Fen-Yu
    Liu, Ming-Chi
    Liu, Chia-Wen
    Tseng, Mei-Hsuan
    Huang, Chi-Fei
    Tien, Hwei-Fang
    [J]. BLOOD, 2010, 115 (14) : 2749 - 2754
  • [5] Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    Dang, Lenny
    White, David W.
    Gross, Stefan
    Bennett, Bryson D.
    Bittinger, Mark A.
    Driggers, Edward M.
    Fantin, Valeria R.
    Jang, Hyun Gyung
    Jin, Shengfang
    Keenan, Marie C.
    Marks, Kevin M.
    Prins, Robert M.
    Ward, Patrick S.
    Yen, Katharine E.
    Liau, Linda M.
    Rabinowitz, Joshua D.
    Cantley, Lewis C.
    Thompson, Craig B.
    Heiden, Matthew G. Vander
    Su, Shinsan M.
    [J]. NATURE, 2009, 462 (7274) : 739 - U52
  • [6] Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
    Figueroa, Maria E.
    Abdel-Wahab, Omar
    Lu, Chao
    Ward, Patrick S.
    Patel, Jay
    Shih, Alan
    Li, Yushan
    Bhagwat, Neha
    Vasanthakumar, Aparna
    Fernandez, Hugo F.
    Tallman, Martin S.
    Sun, Zhuoxin
    Wolniak, Kristy
    Peeters, Justine K.
    Liu, Wei
    Choe, Sung E.
    Fantin, Valeria R.
    Paietta, Elisabeth
    Lowenberg, Bob
    Licht, Jonathan D.
    Godley, Lucy A.
    Delwel, Ruud
    Valk, Peter J. M.
    Thompson, Craig B.
    Levine, Ross L.
    Melnick, An
    [J]. CANCER CELL, 2010, 18 (06) : 553 - 567
  • [7] IDH2 Mutations in Patients with D-2-Hydroxyglutaric Aciduria
    Kranendijk, Martijn
    Struys, Eduard A.
    van Schaftingen, Emile
    Gibson, K. Michael
    Kanhai, Warsha A.
    van der Knaap, Marjo S.
    Amiel, Jeanne
    Buist, Neil R.
    Das, Anibh M.
    de Klerk, Johannis B.
    Feigenbaum, Annette S.
    Grange, Dorothy K.
    Hofstede, Floris C.
    Holme, Elisabeth
    Kirk, Edwin P.
    Korman, Stanley H.
    Morava, Eva
    Morris, Andrew
    Smeitink, Jan
    Sukhai, Ram N.
    Vallance, Hilary
    Jakobs, Cornelis
    Salomons, Gajja S.
    [J]. SCIENCE, 2010, 330 (6002) : 336 - 336
  • [8] IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
    Marcucci, Guido
    Maharry, Kati
    Wu, Yue-Zhong
    Radmacher, Michael D.
    Mrozek, Krzysztof
    Margeson, Dean
    Holland, Kelsi B.
    Whitman, Susan P.
    Becker, Heiko
    Schwind, Sebastian
    Metzeler, Klaus H.
    Powell, Bayard L.
    Carter, Thomas H.
    Kolitz, Jonathan E.
    Wetzler, Meir
    Carroll, Andrew J.
    Baer, Maria R.
    Caligiuri, Michael A.
    Larson, Richard A.
    Bloomfield, Clara D.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (14) : 2348 - 2355
  • [9] IDH1 and IDH2 Mutations Are Frequent Genetic Alterations in Acute Myeloid Leukemia and Confer Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia With NPM1 Mutation Without FLT3 Internal Tandem Duplication
    Paschka, Peter
    Schlenk, Richard F.
    Gaidzik, Verena I.
    Habdank, Marianne
    Kroenke, Jan
    Bullinger, Lars
    Spaeth, Daniela
    Kayser, Sabine
    Zucknick, Manuela
    Goetze, Katharina
    Horst, Heinz-A.
    Germing, Ulrich
    Doehner, Hartmut
    Doehner, Konstanze
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (22) : 3636 - 3643
  • [10] Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas
    Sanson, Marc
    Marie, Yannick
    Paris, Sophie
    Idbaih, Ahmed
    Laffaire, Julien
    Ducray, Francois
    El Hallani, Soufiane
    Boisselier, Blandine
    Mokhtari, Karima
    Hoang-Xuan, Khe
    Delattre, Jean-Yves
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (25) : 4150 - 4154
12