Persistence of mutant isocitrate dehydrogenase in patients with acute myeloid leukemia in remission

被引：18

作者：

Chou, W-C ^{[1
,2
]}

Peng, K-Y ^{[3
,4
]}

Lei, W-C ^{[2
]}

Ko, B-S ^{[2
]}

Tsay, W. ^{[2
]}

Kuo, C-H ^{[3
,5
]}

Tien, H-F ^{[2
]}

机构：

[1] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Lab Med, Taipei 10764, Taiwan

[2] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Div Hematol, Taipei 10764, Taiwan

[3] Natl Taiwan Univ, Ctr Genom Med, Metabol Core Lab, Taipei 10764, Taiwan

[4] Natl Taiwan Univ, Coll Publ Hlth, Inst Environm Hlth, Taipei 10764, Taiwan

[5] Natl Taiwan Univ, Coll Med, Dept Pharm, Taipei 10764, Taiwan

来源：

LEUKEMIA | 2012年 / 26卷 / 03期

关键词：

INTERNAL TANDEM DUPLICATION; IDH2; MUTATIONS; BEARING; GLIOMAS;

D O I：

10.1038/leu.2011.215

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：527 / 529

页数：3

共 15 条

[1] Sensitive measurement of quantity dynamics of FLT3 internal tandem duplication at early time points provides prognostic information [J].

Chou, W. -C. ;

Hou, H. -A. ;

Liu, C. -Y. ;

Chen, C. -Y. ;

Lin, L. -I. ;

Huang, Y. -N. ;

Chao, Y. -C. ;

Hsu, C. -A. ;

Huang, C. -F. ;

Tien, H. -F. .

ANNALS OF ONCOLOGY, 2011, 22 (03) :696-704

[2] Clinical implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nucleophosmin (NPM1) mutations [J].

Chou, W-C ;

Tang, J-L ;

Wu, S-J ;

Tsay, W. ;

Yao, M. ;

Huang, S-Y ;

Huang, K-C ;

Chen, C-Y ;

Huang, C-F ;

Tien, H-F .

LEUKEMIA, 2007, 21 (05) :998-1004

[3] The prognostic impact and stability of Isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia [J].

Chou, W-C ;

Lei, W-C ;

Ko, B-S ;

Hou, H-A ;

Chen, C-Y ;

Tang, J-L ;

Yao, M. ;

Tsay, W. ;

Wu, S-J ;

Huang, S-Y ;

Hsu, S-C ;

Chen, Y-C ;

Chang, Y-C ;

Kuo, K-T ;

Lee, F-Y ;

Liu, M-C ;

Liu, C-W ;

Tseng, M-H ;

Huang, C-F ;

Tien, H-F .

LEUKEMIA, 2011, 25 (02) :246-253

[4] Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation [J].

Chou, Wen-Chien ;

Hou, Hsin-An ;

Chen, Chien-Yuan ;

Tang, Jih-Luh ;

Yao, Ming ;

Tsay, Woei ;

Ko, Bor-Shen ;

Wu, Shang-Ju ;

Huang, Shang-Yi ;

Hsu, Szu-Chun ;

Chen, Yao-Chang ;

Huang, Yen-Ning ;

Chang, Yi-Chang ;

Lee, Fen-Yu ;

Liu, Ming-Chi ;

Liu, Chia-Wen ;

Tseng, Mei-Hsuan ;

Huang, Chi-Fei ;

Tien, Hwei-Fang .

BLOOD, 2010, 115 (14) :2749-2754

[5] Cancer-associated IDH1 mutations produce 2-hydroxyglutarate [J].

Dang, Lenny ;

White, David W. ;

Gross, Stefan ;

Bennett, Bryson D. ;

Bittinger, Mark A. ;

Driggers, Edward M. ;

Fantin, Valeria R. ;

Jang, Hyun Gyung ;

Jin, Shengfang ;

Keenan, Marie C. ;

Marks, Kevin M. ;

Prins, Robert M. ;

Ward, Patrick S. ;

Yen, Katharine E. ;

Liau, Linda M. ;

Rabinowitz, Joshua D. ;

Cantley, Lewis C. ;

Thompson, Craig B. ;

Heiden, Matthew G. Vander ;

Su, Shinsan M. .

NATURE, 2009, 462 (7274) :739-U52

[6] Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation [J].

Figueroa, Maria E. ;

Abdel-Wahab, Omar ;

Lu, Chao ;

Ward, Patrick S. ;

Patel, Jay ;

Shih, Alan ;

Li, Yushan ;

Bhagwat, Neha ;

Vasanthakumar, Aparna ;

Fernandez, Hugo F. ;

Tallman, Martin S. ;

Sun, Zhuoxin ;

Wolniak, Kristy ;

Peeters, Justine K. ;

Liu, Wei ;

Choe, Sung E. ;

Fantin, Valeria R. ;

Paietta, Elisabeth ;

Lowenberg, Bob ;

Licht, Jonathan D. ;

Godley, Lucy A. ;

Delwel, Ruud ;

Valk, Peter J. M. ;

Thompson, Craig B. ;

Levine, Ross L. ;

Melnick, An .

CANCER CELL, 2010, 18 (06) :553-567

[7] IDH2 Mutations in Patients with D-2-Hydroxyglutaric Aciduria [J].

Kranendijk, Martijn ;

Struys, Eduard A. ;

van Schaftingen, Emile ;

Gibson, K. Michael ;

Kanhai, Warsha A. ;

van der Knaap, Marjo S. ;

Amiel, Jeanne ;

Buist, Neil R. ;

Das, Anibh M. ;

de Klerk, Johannis B. ;

Feigenbaum, Annette S. ;

Grange, Dorothy K. ;

Hofstede, Floris C. ;

Holme, Elisabeth ;

Kirk, Edwin P. ;

Korman, Stanley H. ;

Morava, Eva ;

Morris, Andrew ;

Smeitink, Jan ;

Sukhai, Ram N. ;

Vallance, Hilary ;

Jakobs, Cornelis ;

Salomons, Gajja S. .

SCIENCE, 2010, 330 (6002) :336-336

[8] IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study [J].

Marcucci, Guido ;

Maharry, Kati ;

Wu, Yue-Zhong ;

Radmacher, Michael D. ;

Mrozek, Krzysztof ;

Margeson, Dean ;

Holland, Kelsi B. ;

Whitman, Susan P. ;

Becker, Heiko ;

Schwind, Sebastian ;

Metzeler, Klaus H. ;

Powell, Bayard L. ;

Carter, Thomas H. ;

Kolitz, Jonathan E. ;

Wetzler, Meir ;

Carroll, Andrew J. ;

Baer, Maria R. ;

Caligiuri, Michael A. ;

Larson, Richard A. ;

Bloomfield, Clara D. .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (14) :2348-2355

[9] IDH1 and IDH2 Mutations Are Frequent Genetic Alterations in Acute Myeloid Leukemia and Confer Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia With NPM1 Mutation Without FLT3 Internal Tandem Duplication [J].

Paschka, Peter ;

Schlenk, Richard F. ;

Gaidzik, Verena I. ;

Habdank, Marianne ;

Kroenke, Jan ;

Bullinger, Lars ;

Spaeth, Daniela ;

Kayser, Sabine ;

Zucknick, Manuela ;

Goetze, Katharina ;

Horst, Heinz-A. ;

Germing, Ulrich ;

Doehner, Hartmut ;

Doehner, Konstanze .

JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (22) :3636-3643

[10] Isocitrate Dehydrogenase 1 Codon 132 Mutation Is an Important Prognostic Biomarker in Gliomas [J].

Sanson, Marc ;

Marie, Yannick ;

Paris, Sophie ;

Idbaih, Ahmed ;

Laffaire, Julien ;

Ducray, Francois ;

El Hallani, Soufiane ;

Boisselier, Blandine ;

Mokhtari, Karima ;

Hoang-Xuan, Khe ;

Delattre, Jean-Yves .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (25) :4150-4154

← 1 2 →