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Recovery of state-specific potential of molecular motor from single-molecule trajectory
被引:26
作者:
Toyabe, Shoichi
[1
,2
]
Ueno, Hiroshi
[1
]
Muneyuki, Eiro
[1
]
机构:
[1] Chuo Univ, Fac Sci & Engn, Tokyo 1128551, Japan
[2] Univ Munich, Fac Phys, D-80339 Munich, Germany
来源:
基金:
日本科学技术振兴机构;
关键词:
F-1-ATPASE;
ATP;
RESOLUTION;
ROTATION;
HYDROLYSIS;
CATALYSIS;
ENERGY;
D O I:
10.1209/0295-5075/97/40004
中图分类号:
O4 [物理学];
学科分类号:
0702 ;
摘要:
We have developed a novel method to evaluate the potential profile of a molecular motor at each chemical state from only the probe's trajectory and applied it to a rotary molecular motor F1-ATPase. By using this method, we could also obtain the information regarding the mechanochemical coupling and energetics. We demonstrate that the position-dependent transition of the chemical states is the key feature for the highly efficient free-energy transduction by F1-ATPase. Copyright (C) EPLA, 2012
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页数:6
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