Recovery of state-specific potential of molecular motor from single-molecule trajectory

被引：26

作者：

Toyabe, Shoichi ^{[1
,2
]}

Ueno, Hiroshi ^{[1
]}

Muneyuki, Eiro ^{[1
]}

机构：

[1] Chuo Univ, Fac Sci & Engn, Tokyo 1128551, Japan

[2] Univ Munich, Fac Phys, D-80339 Munich, Germany

来源：

EPL | 2012年 / 97卷 / 04期

基金：

日本科学技术振兴机构;

关键词：

F-1-ATPASE; ATP; RESOLUTION; ROTATION; HYDROLYSIS; CATALYSIS; ENERGY;

D O I：

10.1209/0295-5075/97/40004

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We have developed a novel method to evaluate the potential profile of a molecular motor at each chemical state from only the probe's trajectory and applied it to a rotary molecular motor F1-ATPase. By using this method, we could also obtain the information regarding the mechanochemical coupling and energetics. We demonstrate that the position-dependent transition of the chemical states is the key feature for the highly efficient free-energy transduction by F1-ATPase. Copyright (C) EPLA, 2012

引用

页数：6

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