Organ Preservation in Rectal Cancer

被引：17

作者：

Yuval, Jonathan B. ^{[1
]}

Thompson, Hannah M. ^{[1
]}

Garcia-Aguilar, Julio ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Surg, 1275 York Ave, New York, NY 10021 USA

来源：

JOURNAL OF GASTROINTESTINAL SURGERY | 2020年 / 24卷 / 08期

关键词：

Nonoperative management; Watch-and-wait; Rectal cancer; Organ preservation; SHORT-COURSE RADIOTHERAPY; CLINICAL COMPLETE RESPONDERS; TOTAL MESORECTAL EXCISION; COURSE RADIATION-THERAPY; PREOPERATIVE CHEMORADIATION; NEOADJUVANT CHEMORADIATION; NONOPERATIVE MANAGEMENT; RANDOMIZED-TRIAL; TUMOR RESPONSE; STOCKHOLM III;

D O I：

10.1007/s11605-020-04583-w

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A proportion of patients with rectal cancer who undergo neoadjuvant treatment end up with a complete pathological response. Because these patients have excellent oncological outcomes, many have questioned if surgical treatment in this population constitutes overtreatment. There is growing interest in watch and wait with selective organ preservation for rectal cancer patients. We review the fundamentals and key considerations of this approach including patient selection, available treatment regimens, assessment of response, long-term monitoring of response, and long-term oncological and functional outcomes.

引用

页码：1880 / 1888

页数：9

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