Ethanolic Extract of Eucheuma cottonii Promotes in vivo Hair Growth and Wound Healing

被引:0
|
作者
Fard, Samaneh Ghasemi [1 ]
Shamsabadi, Fatemeh Tash [2 ]
Emadi, Mozhdeh [3 ]
Meng, Goh Yong [4 ]
Muhammad, Kharidah [1 ]
Mohamed, Suhaila [1 ]
机构
[1] Univ Putra Malaysia, Fac Food Sci & Technol, Serdang 43400, Selangor, Malaysia
[2] Univ Putra Malaysia, Inst Biosci, Serdang 43400, Selangor, Malaysia
[3] Univ Putra Malaysia, Dept Anim Sci, Fac Agr, Serdang 43400, Selangor, Malaysia
[4] Univ Putra Malaysia, Fac Vet Med, Serdang 43400, Selangor, Malaysia
来源
JOURNAL OF ANIMAL AND VETERINARY ADVANCES | 2011年 / 10卷 / 05期
关键词
Seaweed (Eucheuma cottonii); hair growth; wound healing; ethanolic extract; antioxidant; ascertaining; ANTIOXIDANT ACTIVITIES; FOLLICLE; SEAWEEDS; VITRO; CELLS;
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Hair is considered to be a major component of an individual's general appearance. It is also psychosocial important and patients both men and women with hair loss (alopecia) often deeply suffer. Demand for medications that alter hair growth and appearance has led to a multibillion-dollar industry and thus far few natural effective products are available. For the purpose of ascertaining natural products which possess hair growing activity we looked over onto ethanolic and aqueous extracts of E. cottonii. Hair follicle epithelial stem cells and their contribution to skin healing have attracted particular attention. Oral treatments commenced soon after shaving the dorsal interscapular area of healthy male Sprague-Dawley rats. Microscopic observations of skin were performed. This study showed ethanolic extract of E. cottonii enhanced hair growth by higher proliferative activity. Ethanolic extract of this seaweed in. creased the rate of wound contraction and epithelization when compared to positive and negative control groups. The ethanolic extract of E. cottonii was approximately 20% more effective than aqueous extraction. The extraction also possesses several antioxidant compounds which may be responsible for the accelerated hair growth and wound healing. We demonstrated for the first time in. the present study that this seaweed extracts revealed faster healing and hair growth even when compared with positive control group.
引用
收藏
页码:601 / 605
页数:5
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