Nondigestible Oligosaccharides with Anti-Obesity Effects

被引：53

作者：

Liu, Yongjian ^{[1
,2
]}

Chen, Jiajia ^{[1
,2
]}

Tan, Qiuhua ^{[1
,2
]}

Deng, Xiaoyi ^{[1
,2
]}

Tsa, Ping-Ju ^{[3
]}

Chen, Pei-Hsuan ^{[3
]}

Ye, Manxiang ^{[4
]}

Guo, Jiao ^{[2
]}

Su, Zhengquan ^{[1
]}

机构：

[1] Guangdong Pharmaceut Univ, Guangdong Prov Univ Engn Technol Res Ctr Nat Prod, Guangdong Engn Res Ctr Nat Prod & New Drugs, Guangzhou 510006, Peoples R China

[2] Guangdong Pharmaceut Univ, Guangdong Metab Dis Res Ctr Integrated Chinese &, Guangzhou 510006, Peoples R China

[3] King Prebiot Biotechnol TVV CO LTD, New Taipei 24446, Taiwan

[4] New Francisco Yunfu City Biotechnol CO LTD, Yunfu City 527343, Guangdong, Peoples R China

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2020年 / 68卷 / 01期

关键词：

oligosaccharides; obesity; intestinal microbiota; HIGH-FAT DIET; IN-VITRO FERMENTATION; GUT MICROBIOTA; ISOMALTO-OLIGOSACCHARIDES; GALACTO-OLIGOSACCHARIDES; BILE-ACIDS; FERULOYLATED OLIGOSACCHARIDES; CHITOSAN OLIGOSACCHARIDE; MARINE POLYSACCHARIDES; GLUCOSE-METABOLISM;

D O I：

10.1021/acs.jafc.9b06079

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Obesity has an important influence on health conditions, causing a multitude of complications and comorbidities, and drug therapy is considered to be one of the treatment strategies. Nowadays, there is increasing interest in the study of intestinal microbiota regulation of obesity; also, an increasing number of agricultural and sideline products have been found to have anti-obesity potential. In the present review, we summarize an overview of current known and potential anti-obesity oligosaccharides and their molecular structures. We describe their anti-obesity potential activity and the molecular structure associated with this activity, the regulation of intestinal microbiota composition and its mechanism of action, including regulation of the short-chain fatty acid (SCFA) pathway and altering bile acid (BA) pathway. This review will provide new ideas for us to develop new anti-obesity functional foods.

引用

页码：4 / 16

页数：13

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