Towards a truly integrative biology through the functional genomics of yeast

被引:50
作者
Delneri, D
Brancia, FL
Oliver, SG
机构
[1] Univ Manchester, Sch Biol Sci, Manchester M13 9PT, Lancs, England
[2] UMIST, Michael Barber Ctr Mass Spectrometry, Manchester M60 1QD, Lancs, England
基金
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词
D O I
10.1016/S0958-1669(00)00179-8
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A complete library of mutant Saccharomyces cerevisiae strains, each deleted for a single representative of yeast's 6000 protein-encoding genes, has been constructed. This represents a major biological resource for the study of eukaryotic functional genomics. However, yeast is also being used as a test-bed for the development of functional genomic technologies at all levels of analysis, including the transcriptome, proteome and metabolome.
引用
收藏
页码:87 / 91
页数:5
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