Diastereoselective synthesis of (2S,3R)- and (2R,3R)-2,6-dimethyl-2-homoprenyl-chroman-3-ol

被引：0

作者：

Inoue, S ^{[1
]}

Asami, M ^{[1
]}

Honda, K ^{[1
]}

Shrestha, KS ^{[1
]}

Takahashi, M ^{[1
]}

Yoshino, T ^{[1
]}

机构：

[1] Yokohama Natl Univ, Fac Engn, Dept Synthet Chem, Yokohama, Kanagawa 2408501, Japan

来源：

SYNLETT | 1998年 / 06期

关键词：

chroman; ortho-alkylation; diastereoselective synthesis; 2,3]sigmatropic rearrangement;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereoselective synthesis of (2S*,3R*)- and (2R*,3R*)-2,2-dialkylchroman-3-ols was achieved by stereoselective epoxide-opening cyclization of ortho-(2,3-epoxyalkyl)phenols which were prepared by the coupling of p-cresol and (2R*,3R*)- and (2R*,3S*)-2,3-diacetoxyalkyl isopropyl sulfides, which were in turn derived from geraniol and nerol, respectively.

引用

页码：679 / +

页数：4

共 17 条

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Diastereoselective synthesis of (2S*,3R*)- and (2R*,3R*)-2,6-dimethyl-2-homoprenyl-chroman-3-ol

Diastereoselective synthesis of (2S,3R)- and (2R,3R)-2,6-dimethyl-2-homoprenyl-chroman-3-ol