Antibacterial and antiproliferative activity of cationic fullerene derivatives

被引：122

作者：

Mashino, T

Nishikawa, D

Takahashi, K

Usui, N

Yamori, T

Seki, M

Endo, T

Mochizuki, M

机构：

[1] Kyoritsu Coll Pharmaceut Sci, Minato Ku, Tokyo 1058512, Japan

[2] Japanese Fdn Canc Res, Toshima Ku, Tokyo 1708455, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 24期

关键词：

D O I：

10.1016/j.bmcl.2003.09.040

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We examined the antibacterial and antiproliferative activities of alkylated C-60-bis(N,N-dimethylpyrrolidinium iodide) derivatives. The fullerene derivatives inhibited bacteria and cancer cell growth effectively. However, the fullerene derivatives with a long alkyl chain did not show antibacterial activity. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：4395 / 4397

页数：3

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