The relationship between lifetime suicide attempts, serum lipid levels, and metabolic syndrome in patients with bipolar disorders

被引:22
作者
Shakeri, Jalal [1 ]
Farnia, Vahid [1 ]
Valinia, Katayoun [2 ]
Hashemian, Amir Hossein [3 ]
Bajoghli, Hafez [4 ,5 ]
Holsboer-Trachsler, Edith [6 ]
Brand, Serge [6 ,7 ]
机构
[1] Kermanshah Univ Med Sci, Dept Psychiat, Behav Sci Res Ctr, Kermanshah, Iran
[2] Kermanshah Univ Med Sci, Student Res Ctr, Kermanshah, Iran
[3] Kermanshah Univ Med Sci, Sch Publ Hlth, Dept Biostat & Epidemiol, Kermanshah, Iran
[4] Univ Tehran Med Sci, INCAS, Iranian Inst Reduct High Risk Behav, Tehran, Iran
[5] Mahidol Univ, ASEAN Inst Hlth Dev, Nakhornpathom, Thailand
[6] Univ Basel, Psychiat Clin, Ctr Affect Stress & Sleep Disorders, CH-4012 Basel, Switzerland
[7] Univ Basel, Div Sport Sci, Dept Exercise & Hlth Sci, Fac Med, CH-4012 Basel, Switzerland
关键词
Lifetime suicide attempts; bipolar disorder; metabolic syndrome; serum lipid profiles; CHOLESTEROL LEVELS; MAJOR DEPRESSION; BEHAVIOR; RISK; ASSOCIATION; COMORBIDITY;
D O I
10.3109/13651501.2014.988271
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objectives. To assess the relationship between lifetime suicide attempts (SAs), serum lipid values, and metabolic syndrome (MetS) in patients with bipolar disorders (BPD). Methods. Eighty patients with BPD took part in the study (M = 40.60 years). Aft er psychiatric diagnosis, demographic data, SAs, and serum lipids were measured and MetS was calculated. Results. 70% reported at least one suicide attempt. 52.5% suffered from MetS. Suicide attempters had higher cholesterol values. SAs were associated with a family history of suicide, current mood state, and lower educational level. SAs were unrelated to MetS. Conclusions. In patients with BPD, against expectations, the occurrence of SAs was associated with higher cholesterol values. Serum lipid values are not suitable as a biological trait marker to predict SAs.
引用
收藏
页码:124 / 131
页数:8
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