Coronavirus disease 2019 in Latin American patients with multiple sclerosis

被引：9

作者：

Fragoso, Yara D. ^{[1
]}

Schiavetti, Irene ^{[2
]}

Carmisciano, Luca ^{[2
]}

Ponzano, Marta ^{[2
]}

Steinberg, Judith ^{[3
]}

Trevino-Frenk, Irene ^{[4
]}

Ciampi, Ethel ^{[5
]}

Vecino, Maria Cecilia A. ^{[6
]}

Correa, Edgar P. ^{[7
]}

Carcamo, Claudia ^{[8
]}

Gomes, Sidney ^{[9
]}

Pimentel, Maria Lucia V. ^{[10
]}

Santos, Gutemberg A. C. ^{[11
,12
]}

Vrech, Carlos ^{[13
]}

Winckler, Thereza C. A. ^{[14
]}

Sormani, Maria Pia ^{[2
,15
]}

机构：

[1] Univ Metropolitana Santos, Dept Post Grad Studies, Ave Conselheiro Nebias 536, BR-11045002 Santos, SP, Brazil

[2] Univ Genoa, Sect Biostat, Dept Hlth Sci, Genoa, Italy

[3] Hosp Britan, Dept Neurol, Buenos Aires, DF, Argentina

[4] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Mexico City, DF, Mexico

[5] Hosp Dr Sotero del Rio, Dept Neurol, Santiago, Chile

[6] Hosp Moinhos de Vento, Dept Neurol, Porto Alegre, RS, Brazil

[7] Hosp Carlos Andrade Marin, Dept Neurol, Quito, Ecuador

[8] Univ Catolica Chile, Dept Neurol, Santiago, Chile

[9] Hosp Beneficencia Portuguesa Sao Paulo, Dept Neurol, Sao Paulo, SP, Brazil

[10] Santa Casa Misericordia Rio de Janeiro, Dept Neurol, Rio De Janeiro, RJ, Brazil

[11] Univ Estacio Sa, Dept Neurol, Rio De Janeiro, RJ, Brazil

[12] Univ Fed Fluminense, Rio De Janeiro, RJ, Brazil

[13] Sanatorio Allende, Dept Neurol, Cordoba, Argentina

[14] Private Neurol Clin, Curitiba, PR, Brazil

[15] IRCCS Osped Policlin San Martino, Genoa, Italy

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2021年 / 55卷

关键词：

Multiple sclerosis; Pandemic; COVID-19; rituximab; ocrelizumab;

D O I：

10.1016/j.msard.2021.103173

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Patients with multiple sclerosis (MS) who present coronavirus disease 2019 (COVID-19) are of particular interest to neurologists. These patients have a neuroimmune disease and receive immunomodulatory or immunosuppressive therapies in the long-term. We present here data from 73 patients with MS and a confirmed diagnosis of COVID-19 from five Latin American countries. Fifteen patients (20.5%) were hospitalized and two patients died. The use of anti-CD20 therapies was the only risk factor associated to hospitalization and death. Despite the small sample size, this study highlights the awareness regarding therapeutic options for MS during the pandemic.

引用

页数：3

共 8 条

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