Low measles seropositivity rate among children and young adults: A sero-epidemiological study in southern China in 2008

被引：35

作者：

Fu, Chuanxi ^{[1
,2
]}

Xu, Jianxiong ^{[2
]}

Liu, Weibin ^{[3
]}

Zhang, Wei ^{[2
]}

Wang, Ming ^{[2
]}

Nie, Jun ^{[1
]}

Ruediger, von Kries ^{[4
]}

机构：

[1] So Med Univ, Dept Epidemiol, Sch Publ Hlth & Trop Med, Guangzhou 510515, Guangdong, Peoples R China

[2] Guangzhou Ctr Dis Control & Prevent, Guangzhou 510080, Guangdong, Peoples R China

[3] Mayo Clin, Coll Med, Dept Mol Med, Rochester, MN USA

[4] Univ Munich, Div Epidemiol, Inst Social Pediat & Adolescent Med, Munich, Germany

来源：

VACCINE | 2010年 / 28卷 / 51期

关键词：

Measles; Seroprevalence; Immunity; HEPATITIS-B VACCINATION; ELIMINATION; CAMPAIGN; IMMUNITY; REGION; IMPACT; MUMPS;

D O I：

10.1016/j.vaccine.2010.07.071

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To obtain sero-epidemiological profile and develop optimal strategies to promote measles elimination, we conducted a measles seroprevalence study using stratified sampling method in Guangzhou, southern China in 2008. 4036 samples were analyzed by the enzyme-linked immunosorbent assay method and the overall sero-positive rate of measles antibody was 70.6% (95% CI 69.2-72.0%). Positive seroprevalences differed among age groups (P = 0.000) and a W-curve distribution was observed. The 15-29 years group had the low positive rate of 58.8% (95% CI 54.9-62.7%). Catch-up vaccination campaigns should be promoted among susceptible population of <= 29 year olds including women of childbearing age. (c) 2010 Published by Elsevier Ltd.

引用

页码：8219 / 8223

页数：5

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