Ibrutinib blocks Btk-dependent NF-κB and NFAT responses in human macrophages during Aspergillus fumigatus phagocytosis

被引:97
作者
Bercusson, Amelia [1 ]
Colley, Thomas [1 ]
Shah, Anand [1 ]
Warris, Adilia [2 ]
Armstrong-James, Darius [1 ,3 ,4 ]
机构
[1] Imperial Coll London, Natl Heart & Lung Inst, London, England
[2] Univ Aberdeen, MRC Ctr Med Mycol, Aberdeen, Scotland
[3] Imperial Coll London, MRC Ctr Mol Bacteriol & Infect, London, England
[4] Asthma UK Ctr Allerg Mech Asthma, London, England
基金
英国惠康基金;
关键词
KINASE INHIBITORS; ACTIVATION; PATHWAYS; IMMUNITY;
D O I
10.1182/blood-2017-12-823393
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1985 / 1988
页数:4
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