Microwave-Assisted, Pd(0)-Catalyzed Cross-Coupling of Diazirines with Aryl Halides

被引:36
|
作者
Zhao, Xia [1 ,2 ]
Wu, Guojiao [1 ,2 ]
Yan, Chong [1 ,2 ]
Lu, Kui [1 ,2 ]
Li, Hui [1 ,2 ]
Zhang, Yan [1 ,2 ]
Wang, Jianbo [1 ,2 ,3 ]
机构
[1] Peking Univ, BNLMS, Minist Educ, Coll Chem, Beijing 100871, Peoples R China
[2] Peking Univ, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Coll Chem, Beijing 100871, Peoples R China
[3] Chinese Acad Sci, State Key Lab Organometoll Chem, Shanghai 200032, Peoples R China
关键词
CATALYZED CARBENE INSERTION; MU-CARBENE; VINYL HALIDES; COMPLEXES; TOSYLHYDRAZONE; DIAZOESTERS; GENERATION; RHODIUM; DESIGN; COBALT;
D O I
10.1021/ol102434v
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Pd(0)-catalyzed cross-coupling reactions of diazirines with aryl halides under microwave heating conditions afford a series of substituted olefins. A reaction mechanism involving the migratory insertion of the Pd carbene intermediate is proposed.
引用
收藏
页码:5580 / 5583
页数:4
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