A convenient two-step synthesis of Coenzyme Q1

被引：1
|
作者：
Lu, Bin [1 ]
Qiu, Yong-Fu [1 ]
Qi, Shi [1 ]
Wang, Jin [1 ,2 ]
机构：
[1] Yancheng Teachers Univ, Sch Pharm, Jiangsu Key Lab Bioresources Saline Soils, Hope Ave South Rd 2, Yancheng 224007, Jiangsu, Peoples R China
[2] Yale Univ, Dept Chem, New Haven, CT USA
来源：
JOURNAL OF CHEMICAL RESEARCH | 2019年 / 43卷 / 11-12期
基金：
中国国家自然科学基金;
关键词：
3; 4; 5-trimethoxytoluene; chain reaction; Coenzyme Q; EFFICIENT SYNTHESIS; QUINONES;
D O I：
10.1177/1747519819876524
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A convenient method for the preparation of Coenzyme Q(1) from cheap and readily available 3,4,5-trimethoxytoluene is developed. Coenzyme Q(1) is synthesized in a moderate yield by a two-step procedure involving the key reaction of an allyl bromide with Coenzyme Q(0) through a redox chain reaction. The reaction is efficient and can be used for the synthesis of other Coenzyme Q compounds.
引用
收藏
页码：553 / 556
页数：4
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