Rapidly evolving hepatitis C virus-related cirrhosis in a human immunodeficiency virus-infected patient receiving triple antiretroviral therapy

被引：100
作者：
Zylberberg, H
Pialoux, G
Carnot, P
Landau, A
Bréchot, C
Pol, S
机构：
[1] Hop Necker Enfants Malad, Unite Hepatol, F-75015 Paris, France
[2] Hop Inst Pasteur, Paris, France
[3] Hop Laennec, Lab Anatomopathol, Paris, France
[4] INSERM, U370, Paris, France
来源：
CLINICAL INFECTIOUS DISEASES | 1998年 / 27卷 / 05期
关键词：
D O I：
10.1086/514987
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Triple antiretroviral therapy combining reverse transcriptase and protease inhibitors modifies the prognosis of human immunodeficiency virus (HIV) infection, with dramatic improvement in immune status. The precise impact, if any, of anti-HIV triple therapy on hepatitis C virus (HCV) infection is unknown. We describe an unusual case of rapidly evolving HCV-related cirrhosis that paralleled restoration of immune status in an HIV-infected patient and discuss the possible link between such a severe course of hepatitis C and anti-HIV triple therapy.
引用
收藏
页码：1255 / 1258
页数：4
相关论文
共 14 条
[1]   HEPATITIS-C VIRUS (HCV) GENOTYPE, TISSUE HCV ANTIGENS, HEPATOCELLULAR EXPRESSION OF HLA-A,B,C, AND INTERCELLULAR ADHESION-1 MOLECULES - CLUES TO PATHOGENESIS OF HEPATOCELLULAR DAMAGE AND RESPONSE TO INTERFERON TREATMENT IN PATIENTS WITH CHRONIC HEPATITIS-C [J].
BALLARDINI, G ;
GROFF, P ;
PONTISSO, P ;
GIOSTRA, F ;
FRANCESCONI, R ;
LENZI, M ;
ZAULI, D ;
ALBERTI, A ;
BIANCHI, FB .
JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (05) :2067-2075
[2]   CD8(+) lymphocyte responses to antiretroviral therapy of HIV infection [J].
Carr, A ;
Emery, S ;
Kelleher, A ;
Law, M ;
Cooper, DA .
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1996, 13 (04) :320-326
[3]  
GERBER MA, 1995, J HEPATOL, V22, P83
[4]   FORMULATION AND APPLICATION OF A NUMERICAL SCORING SYSTEM FOR ASSESSING HISTOLOGICAL ACTIVITY IN ASYMPTOMATIC CHRONIC ACTIVE HEPATITIS [J].
KNODELL, RG ;
ISHAK, KG ;
BLACK, WC ;
CHEN, TS ;
CRAIG, R ;
KAPLOWITZ, N ;
KIERNAN, TW ;
WOLLMAN, J .
HEPATOLOGY, 1981, 1 (05) :431-435
[5]   Molecular epidemiology of Bartonella infections in patients with bacillary angiomatosis-peliosis [J].
Koehler, JE ;
Sanchez, MA ;
Garrido, CS ;
Whitfeld, MJ ;
Chen, FM ;
Berger, TG ;
Rodriguez-Barradas, MC ;
LeBoit, PE ;
Tappero, JW .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (26) :1876-1883
[6]   CHOLESTATIC HEPATITIS LEADING TO HEPATIC-FAILURE IN A PATIENT WITH ORGAN-TRANSMITTED HEPATITIS-C VIRUS-INFECTION [J].
LIM, HL ;
LAU, GKK ;
DAVIS, GL ;
DOLSON, DJ ;
LAU, JYN .
GASTROENTEROLOGY, 1994, 106 (01) :248-251
[7]   Antiretroviral drugs for AIDS [J].
Lipsky, JJ .
LANCET, 1996, 348 (9030) :800-803
[8]   RAPIDLY PROGRESSIVE NON-A, NON-B HEPATITIS IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS-INFECTION [J].
MARTIN, P ;
DIBISCEGLIE, AM ;
KASSIANIDES, C ;
LISKERMELMAN, M ;
HOOFNAGLE, JH .
GASTROENTEROLOGY, 1989, 97 (06) :1559-1561
[9]  
Nelson DR, 1997, J IMMUNOL, V158, P1473
[10]   Retrospective analysis of the impact of HIV infection and alcohol use on chronic hepatitis C in a large cohort of drug users [J].
Pol, S ;
Lamorthe, B ;
Thi, NT ;
Thiers, V ;
Carnot, F ;
Zylberberg, H ;
Berthelot, P ;
Bréchot, C ;
Nalpas, B .
JOURNAL OF HEPATOLOGY, 1998, 28 (06) :945-950
12