Cell Biology: Tight Junctions as Biomolecular Condensates

被引：8
|
作者：
Citi, Sandra [1 ]
机构：
[1] Univ Geneva, Fac Sci, Dept Cell Biol, CH-1211 Geneva 4, Switzerland
来源：
CURRENT BIOLOGY | 2020年 / 30卷 / 02期
关键词：
PHASE-SEPARATION; ZO-1; CLAUDINS;
D O I：
10.1016/j.cub.2019.11.060
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two recent studies report that ZO proteins, the main scaffolding proteins of tight junctions, undergo liquid phase separation. This new concept provides understanding at the mechanistic level of how tight junctions are formed and how they participate in mechanochemical signaling in early development.
引用
收藏
页码：R83 / R86
页数：5
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