Hypovitaminosis D as a risk factor of hip fracture severity

被引:37
作者
Larrosa, M. [1 ]
Gomez, A. [1 ]
Casado, E. [1 ]
Moreno, M. [1 ]
Vazquez, I. [1 ]
Orellana, C. [1 ]
Berlanga, E. [2 ]
Ramon, J. [3 ]
Gratacos, J. [1 ]
机构
[1] Univ Inst Parc Tauli UAB, Dept Rheumatol, Barcelona 08208, Spain
[2] Univ Inst Parc Tauli UAB, Lab UDIAT, Ctr Diagnost, Barcelona 08208, Spain
[3] Univ Inst Parc Tauli UAB, Dept Trauma & Orthopaed, Barcelona 08208, Spain
关键词
Functional status; Hip fracture; Hypovitaminosis D; Nutritional status; Osteoporosis; Parathyroid hormone; VITAMIN-D CONCENTRATIONS; FEMORAL-NECK FRACTURES; MORTALITY; MORBIDITY; CALCIUM;
D O I
10.1007/s00198-011-1588-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In a cross-sectional study including 324 patients older than 65 years admitted to our hospital for osteoporotic hip fracture, we found that those patients with a more severe vitamin D deficiency had more severe osteoporotic hip fractures (Garden grades III-IV and Kyle III-IV). To identify possible differences in baseline characteristics of patients with different types of osteoporotic hip fracture. Cross-sectional study including consecutive individuals over 65 admitted to our hospital for osteoporotic hip fracture over a year. Demographic data, fracture type, comorbidities, history of osteoporosis, functional capacity, nutritional status and vitamin D storage were evaluated. We included 324 patients (83 +/- 7 years, 80% women). Two hundred sixteen patients (67%) had vitamin D deficiency (25OHD3 < 25 ng/ml). In patients with severe femoral neck or intertrochanteric fractures (Garden III-IV and Kyle III-IV), vitamin D deficiency was more frequent (74%) and severe (25OHD3 20 +/- 15 ng/ml) than in patients with less severe fractures (57%, 25OHD3 26 +/- 21 ng/ml). Forty-three percent of patients had previous fractures. Only 15% of patients had been previously diagnosed with osteoporosis and 10% were receiving treatment. Patients receiving vitamin D supplements have higher 20OHD3 levels and less severe fractures. Although vitamin D levels are not different between patients with intracapsular or extracapsular hip fractures, a more severe vitamin D deficiency seems to be associated to more severe osteoporotic hip fractures. A prior vitamin D supplementation could avoid a higher severity of these fractures.
引用
收藏
页码:607 / 614
页数:8
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