Electroconvulsive Therapy in Super Refractory Status Epilepticus: Case Series with a Defined Protocol

被引：14

作者：

Garcia-Lopez, Beatriz ^{[1
]}

Isabel Gomez-Menendez, Ana ^{[1
]}

Vazquez-Sanchez, Fernando ^{[2
]}

Perez-Cabo, Eva ^{[3
]}

Isidro-Mesas, Francisco ^{[1
]}

Zabalegui-Perez, Arturo ^{[3
]}

Munoz-Siscart, Ignacio ^{[4
]}

Carmen Lloria-Gil, Maria ^{[1
]}

Soto-Camara, Raul ^{[5
]}

Gonzalez-Bernal, Jeronimo J. ^{[5
]}

Gonzalez-Santos, Josefa ^{[5
]}

Aguilar-Parra, Jose M. ^{[6
]}

Trigueros, Ruben ^{[6
]}

Lopez-Liria, Remedios ^{[7
]}

Kjaer, Troels Wesenberg ^{[8
]}

机构：

[1] Burgos Univ Hosp, Neurophysiol Dept, Burgos 09006, Spain

[2] Burgos Univ Hosp, Neurol Dept, Burgos 09006, Spain

[3] Burgos Univ Hosp, Intens Care Unit, Burgos 09006, Spain

[4] Burgos Univ Hosp, Psychiat Dept, Burgos 09006, Spain

[5] Univ Burgos, Dept Hlth Sci, Burgos 09001, Spain

[6] Univ Almeria, Hlth Res Ctr, Dept Psychol, Almeria 04120, Spain

[7] Univ Almeria, Hlth Res Ctr, Dept Nursing Physiotherapy & Med, Almeria 04120, Spain

[8] SjaellandsUniv Hosp, DK-4000 Roskilde, Denmark

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2020年 / 17卷 / 11期

关键词：

electroconvulsive therapy; ECT; super refractory status epilepticus; antiepileptic treatment; EEG TERMINOLOGY; MORTALITY; EPIDEMIOLOGY; CRITERIA; ADULTS;

D O I：

10.3390/ijerph17114023

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Super-refractory status epilepticus (SRSE) represents a neurological emergency that is characterized by a lack of response to the third line of antiepileptic treatment, including intravenous general anesthetics. It is a medical challenge with high morbidity and mortality. Electroconvulsive therapy (ECT) has been recommended as a nonpharmacologic option of treatment after other alternatives are unsuccessful. Its effect on the cessation of SRSE has been minimally investigated. The objective of this article is to analyze the effect of ECT on SRSE. For this purpose, a multidisciplinary team created a protocol based on clinical guidelines similar to those described previously by Ray et al. (2017). ECT was applied to six patients with SRSE after the failure of antiepileptic treatment and pharmacologic coma.The objective of each ECT session was to elicit a motor seizure for at least 20 s. SRSE was resolved in all patients after several days of treatment, including ECT as a therapy, without relevant adverse effects. Thus, ECT is an effective and feasible option in the treatment of SRSE, and its place in the algorithm in treatment should be studied due to the uncommon adverse effects and the noninvasive character of the therapy.

引用

页码：1 / 11

页数：11

共 38 条

[1]

Ahmed J, 2018, J ECT, V34, pe5, DOI [10.1097/YCT.0000000000000453, 10.1097/YCT.0000000000000450]

[2] Treatment of Super-Refractory Status Epilepticus [J].

Bayrlee, Ahmad ;

Ganeshalingam, Nimalya ;

Kurczewski, Lisa ;

Brophy, Gretchen M. .

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2015, 15 (10)

[3] Burden of illness for super-refractory status epilepticus patients [J].

Beg, Jamil M. ;

Anderson, Thomas D. ;

Francis, Kevin ;

Meckley, Lisa M. ;

Fitzhenry, David ;

Foster, Todd ;

Sukhtankar, Susheel ;

Kanes, Stephen J. ;

Moura, Lidia M. V. R. .

JOURNAL OF MEDICAL ECONOMICS, 2017, 20 (01) :45-53

[4] Unified EEG terminology and criteria for nonconvulsive status epilepticus [J].

Beniczky, Sandor ;

Hirsch, Lawrence J. ;

Kaplan, Peter W. ;

Pressler, Ronit ;

Bauer, Gerhard ;

Aurlien, Harald ;

Brogger, Jan C. ;

Trinka, Eugen .

EPILEPSIA, 2013, 54 :28-29

[5] Trends in Status Epilepticus-Related Hospitalizations and Mortality Redefined in US Practice Over Time [J].

Betjemann, John P. ;

Josephson, S. Andrew ;

Lowenstein, Daniel H. ;

Burke, James F. .

JAMA NEUROLOGY, 2015, 72 (06) :650-655

[6] First-ever population-based study on status epilepticus in French Island of La Reunion (France) - Incidence and fatality [J].

Bhalla, Devender ;

Tchalla, Achille Edem ;

Mignard, Claude ;

Marin, Benoit ;

Mignard, Didier ;

Jallon, Pierre ;

Preux, Pierre-Marie .

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2014, 23 (09) :769-773

[7] Status epilepticus: pathophysiology and management in adults [J].

Chen, JWY ;

Wasterlain, CG .

LANCET NEUROLOGY, 2006, 5 (03) :246-256

[8] The Epidemiology of Status Epilepticus in the United States [J].

Dham, Bhavpreet S. ;

Hunter, Krystal ;

Rincon, Fred .

NEUROCRITICAL CARE, 2014, 20 (03) :476-483

[9] American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2012 version [J].

Hirsch, L. J. ;

LaRoche, S. M. ;

Gaspard, N. ;

Gerard, E. ;

Svoronos, A. ;

Herman, S. T. ;

Mani, R. ;

Arif, H. ;

Jette, N. ;

Minazad, Y. ;

Kerrigan, J. F. ;

Vespa, P. ;

Hantus, S. ;

Claassen, J. ;

Young, G. B. ;

So, E. ;

Kaplan, P. W. ;

Nuwer, M. R. ;

Fountain, N. B. ;

Drislane, F. W. .

JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2013, 30 (01) :1-27

[10] Proposed consensus definitions for new-onset refractory status epilepticus (NORSE), febrile infection-related epilepsy syndrome (FIRES), and related conditions [J].

Hirsch, Lawrence J. ;

Gaspard, Nicolas ;

van Baalen, Andreas ;

Nabbout, Rima ;

Demeret, Sophie ;

Loddenkemper, Tobias ;

Navarro, Vincent ;

Specchio, Nicola ;

Lagae, Lieven ;

Rossetti, Andrea O. ;

Hocker, Sara ;

Gofton, Teneille E. ;

Abend, Nicholas S. ;

Gilmore, Emily J. ;

Hahn, Cecil ;

Khosravani, Houman ;

Rosenow, Felix ;

Trinka, Eugen .

EPILEPSIA, 2018, 59 (04) :739-744

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