IL-2, IL-6 and IL-8 levels remain unaltered in the course of immunosuppressive therapy after renal transplantation

被引：4
|
作者：
Rysz, Jacek [1 ]
Kocur, Eugeniusz [1 ]
Blaszczak, Robert [1 ]
Bartnicki, Piotr [1 ]
Stolarek, Robert A. [1 ,2 ]
Piechota, Mariusz [3 ,4 ]
机构：
[1] Med Univ Lodz, Dept Family Med 2, PL-90549 Lodz, Poland
[2] Med Univ Lodz, Dept Expt & Clin Physiol, PL-92215 Lodz, Poland
[3] Med Univ Lodz, Univ Hosp Lodz 5, Dept Anaesthesiol, PL-90647 Lodz, Poland
[4] Med Univ Lodz, Univ Hosp Lodz 5, Intens Care Unit, PL-90647 Lodz, Poland
来源：
CENTRAL EUROPEAN JOURNAL OF MEDICINE | 2008年 / 3卷 / 02期
关键词：
cytokines; lymphocytes; transplantation; immune system;
D O I：
10.2478/s11536-008-0011-4
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cytokines regulate the immune reactions elicited by renal transplantation (RT). This study was designed to investigate the blood serum levels of IL-2, IL-6, IL-8 in 25 RT patients (10 female and 15 male, mean 5.4 +/- 2.7 yrs after RT) three times over a six-month period during standard immunosuppressive therapy with cyclosporine A, azathioprine and prednisolone. The levels of IL-2, IL-6 and IL-8 were tested with ELISA Quantikine Human Interleukin Immunoassay (R&D Systems, detection level 7,0.7 and 10 mu g/cm(3), respectively). There was no significant alternation of blood serum levels of IL-2, IL-6 and IL-8 in the study patients.
引用
收藏
页码：199 / 202
页数：4
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