Methotrexate for rheumatoid arthritis patients who are on hemodialysis

被引：12
|
作者：
Al-Hasani, Hasanein [2 ,3 ]
Roussou, Euthalia [1 ,2 ,3 ]
机构：
[1] King George V Mem Hosp, Dept Rheumatol & Rehabil, Ilford IG3 8YB, Essex, England
[2] Barts & London Queen Marys Sch Med & Dent, London E1 2AD, England
[3] Barking Havering & Redbridge Univ Hosp NHS Trust, King George Hosp, Ilford IG3 8YB, Essex, England
来源：
RHEUMATOLOGY INTERNATIONAL | 2011年 / 31卷 / 12期
关键词：
Methotrexate; Rheumatoid arthritis; Hemodialysis; End stage renal failure; LOW-DOSE METHOTREXATE; FACTOR-ALPHA THERAPY; INFLIXIMAB TREATMENT; PERITONEAL-DIALYSIS; PANCYTOPENIA; CHEMOTHERAPY; NEUTROPENIA; AMYLOIDOSIS; SECONDARY; REMOVAL;
D O I：
10.1007/s00296-011-2041-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Methotrexate (MTX) can be toxic to patients suffering from end stage renal disease (ESRD) on hemodialysis even at low doses. This increase in toxicity is more notable in terms of bone marrow suppression in the form of pancytopenia. Many methods of elimination including dialysis itself have been proven ineffective, and alternate treatments with anti-TNF alpha blockers can be considered.
引用
收藏
页码：1545 / 1547
页数：3
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