Total Internal Reflection Ellipsometry Approach for Bloch Surface Waves Biosensing Applications

被引：6

作者：

Buzavaite-Verteliene, Ernesta ^{[1
]}

Maciulis, Vincentas ^{[1
]}

Anulyte, Justina ^{[1
]}

Tolenis, Tomas ^{[1
]}

Baskys, Algirdas ^{[1
,2
]}

Plikusiene, Ieva ^{[1
,3
]}

Balevicius, Zigmas ^{[1
,2
]}

机构：

[1] Ctr Phys Sci & Technol, State Res Inst, Sauletekio Ave 3, LT-10257 Vilnius, Lithuania

[2] Vilnius Gediminas Tech Univ, Fac Elect, Naugarduko St 41, LT-03227 Vilnius, Lithuania

[3] Vilnius Univ, Fac Chem & Geosci, NanoTechnas Ctr Nanotechnol & Mat Sci, Naugarduko Str 24, LT-03225 Vilnius, Lithuania

来源：

BIOSENSORS-BASEL | 2022年 / 12卷 / 08期

关键词：

Bloch surfacewaves; total internal reflection ellipsometry; bovine serumalbumin; biosensing; NANOSTRUCTURES; ADSORPTION; SENSOR;

D O I：

10.3390/bios12080584

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A one-dimensional photonic crystal with an additional TiO2 layer, supporting Bloch surface waves (BSW), was used for enhanced signal sensitivity for the detection of protein interaction. To compare the optical response of BSW and photonic crystals (PC), bovine serum albumin and specific antibodies against bovine serum were used as a model system. The results obtained show the enhanced sensitivity of p- and s-BSW components for the 1D PC sample with an additional TiO2 layer. Furthermore, a higher sensitivity was obtained for the BSW component of p-polarization in the PC sample with an additional TiO2 layer, where the sensitivity of the ellipsometric parameter Psi was five times higher and that of the Delta parameter was eight times higher than those of the PC sample. The capabilities of BSW excitations are discussed from the sensitivity point of view and from the design of advanced biosensing.

引用

页数：10

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