Proximal aortic surgery in the elderly population: Is advanced age a contraindication for surgery?

被引:6
|
作者
Wanamaker, Kelly M. [1 ]
Hirji, Sameer A. [1 ]
Del Val, Fernando Ramirez [1 ]
Yammine, Maroun [1 ]
Lee, Jiyae [1 ]
McGurk, Siobhan [1 ]
Shekar, Prem [1 ]
Kaneko, Tsuyoshi [1 ]
机构
[1] Harvard Med Sch, Brigham & Womens Hosp, Div Cardiac Surg, Dept Surg, Boston, MA USA
关键词
aortic surgery; advanced age; calcified aorta; HYPOTHERMIC CIRCULATORY ARREST; QUALITY-OF-LIFE; VALVE-REPLACEMENT; CARDIAC-SURGERY; PENN CLASSIFICATION; OUTCOMES; DISSECTION; RISK; TRANSCATHETER; OCTOGENARIANS;
D O I
10.1016/j.jtcvs.2018.04.100
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: The study objective was to describe the clinical outcomes of elderly patients undergoing ascending aortic surgery. Methods: Patients aged 70 years or older who underwent ascending aortic surgery between January 2002 and December 2013 were examined. Of 415 included patients, 285 were elderly patients (age 70-79 years) and 130 were very elderly (age >= 80 years). Logistic regression and Cox proportional hazards models were used to evaluate operative mortality and long-term survival, respectively. Results: Surgical indications included aortic aneurysm (63.1%), calcified aorta with need for other cardiac procedure (26.4%), and type A dissection (10.5%). Compared with elderly patients, the very elderly patients had a higher burden of comorbidities and operative mortality (13% vs 7%, P <.04). The very elderly patients were also more likely to be discharged to a rehabilitation facility than home (P <.001). However, risk-adjusted operative mortality and 30-day readmissions rates were similar (P >.05). Kaplan-Meier estimates of survival at 1 and 5 years were 85.6% and 72.6% for elderly patients versus 79.2% and 57.1% for the very elderly patients. Age was a strong risk variable for late mortality in the unadjusted and adjusted analyses. Conclusions: After adjusting for these comorbidities, the cause of aortic disease, and the type of procedure, age was not an independent predictor of operative mortality, but was strongly associated with reduced late survival. Thus, advanced age alone should not be an absolute contraindication for ascending aortic surgery.
引用
收藏
页码:53 / 63
页数:11
相关论文
共 50 条
  • [1] Emergent aortic surgery in octogenarians: is the advanced age a contraindication?
    Castano, Mario
    Gualis, Javier
    Martinez-Comendador, Jose M.
    Martin, Elio
    Maiorano, Pasquale
    Castillo, Laura
    JOURNAL OF THORACIC DISEASE, 2017, 9 : S498 - S507
  • [2] Proximal aortic surgery in the elderly: Is age just a number?
    Blanding, Walker M.
    Balsam, Leora B.
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2019, 157 (01) : 64 - 65
  • [3] Surgery for metastatic spine tumors in the elderly. Advanced age is not a contraindication to surgery!
    Amelot, A.
    Balabaud, L.
    Choi, D.
    Fox, Z.
    Crockard, H. A.
    Albert, T.
    Arts, C. M.
    Buchowski, J. M.
    Bunger, C.
    Chung, C. K.
    Coppes, M. H.
    Depreitere, B.
    Fehlings, M. G.
    Harrop, J.
    Kawahara, N.
    Kim, E. S.
    Lee, C. S.
    Leung, Y.
    Liu, Z. J.
    Martin-Benlloch, J. A.
    Massicotte, E. M.
    Meyer, B.
    Oner, F. C.
    Peul, W.
    Quraishi, N.
    Tokuhashi, Y.
    Tomita, K.
    Ulbricht, C.
    Verlaan, J. J.
    Wang, M.
    Mazel, C.
    SPINE JOURNAL, 2017, 17 (06) : 759 - 767
  • [4] Is increased chronological age a contraindication to debulking surgery for elderly patients with advanced ovarian cancer?
    Park, Soo Jin
    Mun, Jaehee
    Yim, Ga Won
    Lee, Maria
    Chung, Hyun Hoon
    Kim, Jae Weon
    Park, Noh Hyun
    Song, Yong Sang
    Kim, Hee Seung
    JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2022, 42 (07) : 3254 - 3259
  • [5] Elective surgery for ascending aortic aneurysm in the elderly: should there be an age cut-off?
    Peterss, Sven
    Mansour, Ahmed M.
    Zafar, Mohammad A.
    Thombre, Kabir
    Rizzo, John A.
    Ziganshin, Bulat A.
    Darr, Umer M.
    Elefteriades, John A.
    EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2017, 51 (05) : 965 - 970
  • [6] The impact of age on patients undergoing aortic arch surgery: Evidence from a multicenter national registry
    Chung, Jennifer
    Stevens, Louis-Mathieu
    Chu, Michael W. A.
    Dagenais, Francois
    Peterson, Mark D.
    Boodhwani, Munir
    Bozinovski, John
    El-Hamamsy, Ismail
    Yamashita, Michael H.
    Atoui, Rony
    Bittira, Bindu
    Payne, Darrin
    Ouzounian, Maral
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2021, 162 (03) : 759 - +
  • [7] Long-Term Survival of the Very Elderly Undergoing Aortic Valve Surgery
    Likosky, Donald S.
    Sorensen, Meredith J.
    Dacey, Lawrence J.
    Baribeau, Yvon R.
    Leavitt, Bruce J.
    DiScipio, Anthony W.
    Hernandez, Felix, Jr.
    Cochran, Richard P.
    Quinn, Reed
    Helm, Robert E.
    Charlesworth, David C.
    Clough, Robert A.
    Malenka, David J.
    Sisto, Donato A.
    Sardella, Gerald
    Olmstead, Elaine M.
    Ross, Cathy S.
    O'Connor, Gerald T.
    CIRCULATION, 2009, 120 (11) : S127 - S133
  • [8] Elective Ascending Aortic Aneurysm Surgery in the Elderly
    Memis, Feyza
    Thijssen, Carlijn G. E.
    Gokalp, Arjen L.
    Notenboom, Maximiliaan L.
    Meccanici, Frederike
    Mokhles, Mohammad Mostafa
    van Kimmenade, Roland R. J.
    Veen, Kevin M.
    Geuzebroek, Guillaume S. C.
    Sjatskig, Jelena
    ter Woorst, Franciscus J.
    Bekkers, Jos A.
    Takkenberg, Johanna J. M.
    Roos-Hesselink, Jolien W.
    JOURNAL OF CLINICAL MEDICINE, 2023, 12 (05)
  • [9] Frailty and risk in proximal aortic surgery
    Ganapathi, Asvin M.
    Englum, Brian R.
    Hanna, Jennifer M.
    Schechter, Matthew A.
    Gaca, Jeffrey G.
    Hurwitz, Lynne M.
    Hughes, G. Chad
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2014, 147 (01) : 186 - +
  • [10] Should age be a contraindication for degenerative lumbar surgery?
    Perez-Prieto, Daniel
    Lozano-Alvarez, Carlos
    Salo, Guillem
    Molina, Antoni
    Llado, Andreu
    Puig-Verdie, Lluis
    Ramirez-Valencia, Manuel
    EUROPEAN SPINE JOURNAL, 2014, 23 (05) : 1007 - 1012