Crohn's Disease and Stroke in a Young Adult

被引:5
作者
Ogawa, Emina [1 ]
Sakakibara, Ryuji [1 ]
Yoshimatsu, Yasushi [1 ]
Suzuki, Yasuo [1 ]
Mouri, Takayuki [1 ]
Tateno, Fuyuki [1 ]
Kishi, Masahiko [1 ]
Oda, Shunsuke [1 ]
Imamura, Haruki [1 ]
机构
[1] Toho Univ, Sakura Med Ctr, Sakura, Chiba, Japan
关键词
Crohn's disease; stroke; young adult; INFLAMMATORY-BOWEL-DISEASE; THROMBOEMBOLIC EVENTS; PEDIATRIC-PATIENTS; ARTERIAL;
D O I
10.2169/internalmedicine.50.5692
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 36-year-old man with a 21-year history of Crohn's disease suddenly developed left hemiparesis. He did not have atherosclerotic risk factors on admission, but he had marked dehydration which was likely due to prolonged home intravenous hyper-alimentation. Brain MRI revealed lacunar infarction in the right anterior corona radiata. An anticoagulation drug and a free-oxide scavenger successfully reversed his neurological deficits almost completely. Stroke in young adults less than 40 years old is extremely rare; therefore, we conclude that Crohn's disease can be a risk factor for acute ischemic stroke in our case, due most probably to dehydration and other complex mechanisms.
引用
收藏
页码:2407 / 2408
页数:2
相关论文
共 10 条
[1]   Risk of Ischemic Stroke in Patients with Crohn's Disease: A Population-based Nested Case-control Study [J].
Andersohn, Frank ;
Waring, Mark ;
Garbe, Edeltraut .
INFLAMMATORY BOWEL DISEASES, 2010, 16 (08) :1387-1392
[2]   Cerebral Thromboembolic Events in Pediatric Patients with Inflammatory Bowel Disease [J].
Barclay, A. R. ;
Keightley, J. M. ;
Horrocks, I. ;
Garrick, V. ;
McGrogan, P. ;
Russell, R. K. .
INFLAMMATORY BOWEL DISEASES, 2010, 16 (04) :677-683
[3]   The incidence of arterial thromboembolic diseases in inflammatory bowel disease: A population-based study [J].
Bernstein, Charles N. ;
Wajda, Andre ;
Blanchard, James F. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2008, 6 (01) :41-45
[4]  
Calderon R, 1998, P R Health Sci J, V17, P293
[5]   Specificities of inflammatory bowel disease in childhood [J].
Griffiths, AM .
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2004, 18 (03) :509-523
[6]   Therapeutic efficacy of infliximab on patients with short duration of Crohn's disease: A Japanese multicenter survey [J].
Matsumoto, Takayuki ;
Iida, Mitsuo ;
Motoya, Satoshi ;
Haruma, Ken ;
Suzuki, Yasuo ;
Kobayashi, Kiyonori ;
Ito, Hiroaki ;
Miyata, Mitsuki ;
Kusunoki, Masato ;
Chiba, Tsutomu ;
Yamamoto, Shojiro ;
Hibi, Toshifumi .
DISEASES OF THE COLON & RECTUM, 2008, 51 (06) :916-923
[7]   Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease [J].
Scaldaferri, Franco ;
Sans, Miquel ;
Vetrano, Stefania ;
Graziani, Cristina ;
De Cristofaro, Raimondo ;
Gerlitz, Bruce ;
Repici, Alessandro ;
Arena, Vincenzo ;
Malesci, Alberto ;
Panes, Julian ;
Grinnell, Brian W. ;
Danese, Silvio .
JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (07) :1951-1960
[8]   Magnetic resonance angiography in a patient with Crohn's disease associated cerebral vasculitis [J].
Schluter, A ;
Krasnianski, M ;
Krivokuca, M ;
Spielmann, RP ;
Neudecker, S ;
Hirsch, W .
CLINICAL NEUROLOGY AND NEUROSURGERY, 2004, 106 (02) :110-113
[9]   Inflammatory Bowel Disease and Cerebrovascular Arterial and Venous Thromboembolic Events in 4 Pediatric Patients: A Case Series and Review of the Literature [J].
Standridge, Shannon ;
de los Reyes, Emily .
JOURNAL OF CHILD NEUROLOGY, 2008, 23 (01) :59-66
[10]  
Yasaka Masahiro, 2005, Rinsho Shinkeigaku, V45, P842