Oncological-Therapy Related Oral Mucositis as an Interdisciplinary Problem-Literature Review

被引:70
作者
Kusiak, Aida [1 ]
Jereczek-Fossa, Barbara Alicja [2 ,3 ]
Cichonska, Dominika [1 ]
Alterio, Daniela [4 ]
机构
[1] Med Univ Gdansk, Dept Periodontol & Oral Mucosa Dis, PL-80210 Gdansk, Poland
[2] Univ Milan, Dept Oncol & Hematooncol, Milan 20141, Italy
[3] IRCCS, IEO European Inst Oncol, Div Radiotherapy, Milan 20141, Italy
[4] IRCCS, European Inst Oncol, Div Radiat Oncol, Milan 20141, Italy
关键词
oral mucositis; oral cavity; oral mucosa; treatment; LEVEL LASER THERAPY; NECK-CANCER; CHEMORADIATION THERAPY; ECONOMIC OUTCOMES; PART; HEAD; CHEMOTHERAPY; PREVENTION; PALIFERMIN; RADIATION;
D O I
10.3390/ijerph17072464
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Oral mucositis is a toxic side effect of non-surgical cancer treatments: chemotherapy and radiotherapy, which strongly impair quality of life and can not only cause strong pain, but also lead to problems with basic physiological needs as eating and swallowing. Development of oral mucositis is associated with type, dosage, and schedule of radiation or chemotherapy and other factors related to patients. Management of oral mucositis is a valid problem, requiring topical application of anesthetics, coating agents, cryotherapy, low level laser therapy, pharmacological methods as usage of keratinocyte growth factors, supplementation of vitamins, and a proper diet. Another approach to oral mucositis measurement includesphotobiomodulation, which brings analgesic and anti-inflammatory effects.Although oral mucositis is a general health issues, the role of proper dental care is essential. It should include elimination of all potential sources of mucosal injury and microorganisms inhabiting theoral cavity through oral hygiene education, professional management ofdental plaque, and treatment of the caries and periodontium, which are necessary to reduce the risk of inflammation in the oral cavity. This paper describes the possibilities of monitoring oral mucositis, taking into account the latest therapeutic achievements.
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页数:12
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