Recent Development of Cardiac Troponin I Detection

被引：151
作者：
Han, Xu [1 ]
Li, Shanghao [1 ]
Peng, Zhili [1 ]
Othman, Abdelhameed M. [2 ,3 ]
Leblanc, Roger [1 ]
机构：
[1] Univ Miami, Dept Chem, Cox Sci Ctr, 1301 Mem Dr, Coral Gables, FL 33146 USA
[2] Taibah Univ, Fac Sci Yanbu, Dept Chem, POB 344, Medina, Saudi Arabia
[3] Univ Sadat City, Dept Environm Biotechnol, Genet Engn & Biotechnol Inst, Menofia Governorate, Egypt
来源：
ACS SENSORS | 2016年 / 1卷 / 02期
基金：
美国国家科学基金会;
关键词：
cardiac troponin I; detection; colorimetric; fluorescence; paramagnetic; electrochemical; surface plasmon resonance; immunoassay; ACUTE MYOCARDIAL-INFARCTION; PARAMAGNETIC PARTICLES; ANALYTICAL PERFORMANCE; CLINICAL-BIOCHEMISTRY; MAGNETIC IMMUNOASSAY; NATIONAL-ACADEMY; GOLD; MARKERS; ASSAY; NANOPARTICLES;
D O I：
10.1021/acssensors.5b00318
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Cardiovascular disease (CVD) has threatened human lives for decades, and a technique for estimating and healing is still needed. There has been increasing interest in finding CVD diagnostic biomarkers to predict risk. Cardiac troponin I (cTnI) has proven to be a significant biomarker for acute myocardial infarction detection. An immunoassay based biosensor for cTnI can play an important role in diagnosis of CVD. Over the past decades, various methodologies regarding cTnI detection have been studied, including colorimetric, fluorescence, paramagnetic, electrochemical, and surface plasmon resonance. This review will focus more on recent strategies about surface immobilized cTnI detection.
引用
收藏
页码：106 / 114
页数：9
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