Radical rearrangement and transfer reactions in proteins

被引：5
作者：
Schoneich, Christian [1 ]
机构：
[1] Univ Kansas, Dept Pharmaceut Chem, Lawrence, KS 66047 USA
来源：
PROTEIN OXIDATION | 2020年 / 64卷 / 01期
关键词：
INTRAMOLECULAR HYDROGEN-TRANSFER; CYSTEINE THIYL RADICALS; NITROGEN-CENTERED RADICALS; METAL-CATALYZED OXIDATION; AMINO-ACIDS; ATOM TRANSFER; EXCHANGE EQUILIBRIA; CHAIN OXIDATION; H BONDS; PEPTIDES;
D O I：
10.1042/EBC20190046
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Radical rearrangement and transfer reactions play an important role in the chemical modifications of proteins in vivo and in vitro. These reactions depend on protein sequence, as well as structure and dynamics. Frequently, these reactions have well-defined precedents in the organic chemistry literature, but their occurrence in proteins provides a stage for a number of novel and, perhaps, unexpected reaction products. This essay will provide an overview over a few representative examples of radical rearrangement and transfer reactions.
引用
收藏
页码：87 / 96
页数：10
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