Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development

被引：329
作者：
Morin, Xavier [1 ,2 ,3 ]
Bellaiche, Yohanns [4 ,5 ,6 ]
机构：
[1] Ecole Normale Super, Inst Biol, F-75005 Paris, France
[2] CNRS, UMR 8197, F-75005 Paris, France
[3] INSERM, U1024, F-75005 Paris, France
[4] Inst Curie, F-75248 Paris 05, France
[5] CNRS, UMR 3215, F-75248 Paris 05, France
[6] INSERM, U934, F-75248 Paris 05, France
来源：
DEVELOPMENTAL CELL | 2011年 / 21卷 / 01期
关键词：
OUTER SUBVENTRICULAR ZONE; PAR PROTEINS; NEURAL STEM; PLASMA-MEMBRANE; PLANAR POLARITY; CLEAVAGE PLANE; DROSOPHILA NEUROBLASTS; MICROCHAETE LINEAGE; MICROTUBULE GROWTH; FATE DETERMINANTS;
D O I：
10.1016/j.devcel.2011.06.012
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The orientation of the mitotic spindle has been proposed to control cell fate choices, tissue architecture, and tissue morphogenesis. Here, we review the mechanisms regulating the orientation of the axis of division and cell fate choices in classical models of asymmetric cell division. We then discuss the mechanisms of mitotic spindle orientation in symmetric cell divisions and its possible implications in tissue morphogenesis. Many recent studies show that future advances in the field of mitotic spindle orientation will arise from combinations of physical perturbation and modeling with classical genetics and developmental biology approaches.
引用
收藏
页码：102 / 119
页数：18
相关论文
共 146 条
[1]   Exploring the effects of mechanical feedback on epithelial topology [J].
Aegerter-Wilmsen, Tinri ;
Smith, Alister C. ;
Christen, Alix J. ;
Aegerter, Christof M. ;
Hafen, Ernst ;
Basler, Konrad .
DEVELOPMENT, 2010, 137 (03) :499-506
[2]   RIC-8 is required for GPR-1/2-Dependent Gα function during asymmetric division of C-elegans embryos [J].
Afshar, K ;
Willard, FS ;
Colombo, K ;
Johnston, CA ;
McCudden, CR ;
Siderovski, DP ;
Gönczy, P .
CELL, 2004, 119 (02) :219-230
[3]   Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila [J].
Aigouy, Benoit ;
Farhadifar, Reza ;
Staple, Douglas B. ;
Sagner, Andreas ;
Roeper, Jens-Christian ;
Juelicher, Frank ;
Eaton, Suzanne .
CELL, 2010, 142 (05) :773-786
[4]   The orientation of cell divisions determines the shape of Drosophila organs [J].
Baena-López, LA ;
Baonza, A ;
García-Bellido, A .
CURRENT BIOLOGY, 2005, 15 (18) :1640-1644
[5]   Asymmetric localization and function of cell-fate determinants: a fly's view [J].
Bardin, AJ ;
Le Borgne, R ;
Schweisguth, F .
CURRENT OPINION IN NEUROBIOLOGY, 2004, 14 (01) :6-14
[6]   The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila [J].
Bellaïche, Y ;
Beaudoin-Massiani, O ;
Stüttem, I ;
Schweisguth, F .
DEVELOPMENT, 2004, 131 (02) :469-478
[7]   The partner of inscuteable/discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila [J].
Bellaïche, Y ;
Radovic, A ;
Woods, DF ;
Hough, CD ;
Parmentier, ML ;
O'Kane, CJ ;
Bryant, PJ ;
Schweisguth, F .
CELL, 2001, 106 (03) :355-366
[8]   Frizzled regulates localization of cell-fate determinants and mitotic spindle rotation during asymmetric cell division [J].
Bellaïche, Y ;
Gho, M ;
Kaltschmidt, JA ;
Brand, AH ;
Schweisguth, F .
NATURE CELL BIOLOGY, 2001, 3 (01) :50-57
[9]   The Drosophila NuMA homolog mud regulates spindle orientation in asymmetric cell division [J].
Bowman, Sarah K. ;
Neumueller, Ralph A. ;
Novatchkova, Maria ;
Du, Quansheng ;
Knoblich, Juergen A. .
DEVELOPMENTAL CELL, 2006, 10 (06) :731-742
[10]   Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells [J].
Busson, S ;
Dujardin, D ;
Moreau, A ;
Dompierre, J ;
De Mey, JR .
CURRENT BIOLOGY, 1998, 8 (09) :541-544
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