Chiral, porous, hybrid solids for highly enantioselective heterogeneous asymmetric hydrogenation of β-keto esters

被引：181

作者：

Hu, A ^{[1
]}

Ngo, HL ^{[1
]}

Lin, WB ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 48期

关键词：

asymmetric catalysis; hybrid materials; hydrogenation; ruthenium; supported catalysts; zirconium;

D O I：

10.1002/anie.200351264

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Catalytic building blocks: Chiral porous zirconium phosphonates containing Rubinap moieties are synthesized by a molecular building-block approach, and characterized by a variety of techniques. These hybrid solids are used for enantioselective heterogeneous asymmetric hydrogenation of β-keto esters with ee values of up to 95% (see picture). Ready tunability of such a molecular building-block approach promises to lead to useful heterogeneous asymmetric catalysts.

引用

页码：6000 / 6003

页数：4

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